Andrew J. Fisher
Professor
ajfisher@ucdavis.edu

Molecular & Cellular Biology
Chemistry

Office
4A Briggs Hall
530-754-6180

Lab
4 Briggs Hall
530-752-5235


Picture of Andrew J. Fisher
 
Degrees:
1992 PhD Purdue University Biophysics
1987 BS Purdue University Biochemistry
Research Interests:
Mechanistic Structural Biochemistry
Systems of focus include: Sulfate activation, Ferredoxin Dependent Bilin Reductases, & Sialyltransferases.
http://www-crystal.ucdavis.edu/fisher

Department and Center Affiliations:
Department of Chemistry
Department of Molecular and Cellular Biology
CBS Graduate Group Affiliations:
Biophysics  
Graduate Groups not Housed in CBS:
Chemistry  
Publications: Last updated 9/22/2009
  • Stoll, S., Gunn, A., Brynda, M., Sughrue, W., Kohler, A. C., Ozarowski, A., Fisher, A. J., Lagarias, J. C., Britt, R. D. (2009). The structure of the biliverdin radical intermediate in phycocyanobilin:ferredoxin oxidoreductase identified by high-field EPR and DFT. J. Am. Chem. Soc. 131:1986-1995.
  • Gay, S. C., Segel, I. H., and Fisher, A. J. (2009). Crystal structure of the two-domain, hexameric APS kinase from Thiobacillus denitrificans: structural basis for the absence of ATP sulfurylase activity. Acta Crystallogr. D Biol. Crystallogr. 65:1021-1031
  • Yu, Z, Lemongello, D., Segel, I. H., and Fisher, A. J. (2008). Crystal structure of Saccharomyces cerevisiae 3'-Phosphoadenosine-5'-phosphosulfate Reductase complexed with adenosine 3',5'-bisphosphate. Biochemistry. 47:12777–12786
  • Ni, L., Chokhawala, H., Cao, H., Henning, R., Ng, L., Huang, S., Yu, H., Chen, X., and Fisher, A. J. (2007). Crystal structures of Pasteurella multocida sialyltransferase complexes with acceptor and donor analogs reveal substrate binding sites and catalytic mechanism. Biochemistry 46:6288-6298.
  • Tu, S.-L, Rockwell, N. C., Lagarias, J. C., and Fisher, A. J. (2007). Insight into the radical mechanism of phycocyanobilin:ferredoxin oxidoreductase (PcyA) revealed by X-ray crystallography and biochemical measurements. Biochemistry 46:1484-1494.
  • Yu, Z., Lansdon, E. B., Segel, I. H., and Fisher, A.J. (2007). Crystal structure of the Bi-functional ATP Sulfurylase/APS kinase from Chemolithotrophic Thermophile Aquifex aeolicus. J. Mol. Biol. 365:732-743.
Courses:
Che 107A Physical Chemistry for the Life Sciences Fall
Che 217 X-ray Crystal Structure Determination Spring