J. David Furlow
Professor
jdfurlow (at) ucdavis (dot) edu
Neurobiology, Physiology and Behavior
Office
274B Briggs Hall
(530) 754-8609
1992
PhD
University of Wisconsin, Madison
(Biochemistry)
1985
BS
Pennsylvania State University
(Biochemistry)
Postdoctoral Fellow - Carnegie Institution of Washington, Department of Embryology
Molecular basis of hormone action, particularly during development. Analysis of gene expression cascades during morphogenesis. Mechanisms of skeletal muscle atrophy and death.
Molecular basis of hormone action, particularly during development
UCD Cancer Center
Faculty, Physiology course, Marine Biological Laboratory, Woods Hole, MA
The Endocrine Society
Society for Developmental Biology
American Physiological Society
Biochemistry, Molecular, Cellular and Developmental Biology
Molecular, Cellular, and Integrative Physiology
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Denver, RJ, Scanlan TS, and JD Furlow (2009) Thyroid hormone receptor subtype specificity for
hormone-dependent neurogenesis in Xenopus laevis. Developmental Biology (in press).
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Johnsen SA, Güngör C, Prenzel T, Riethdorf, S, Riethdorf L, Taniguchi-Ishigaki N, Rau T, Tursun
B, Furlow JD, Sauter G, Scheffner M, Pantel K, Gannon F, and I Bach. (2009) Identification of
the LIM cofactors CLIM and RLIM as Novel Regulators of Estrogen-Dependent Transcription
in Breast Cancer. Cancer Research. 69:128-136
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Waddell DS, Baehr LM, van der Brandt J, Johnsen SA, Reichardt HM, Furlow JD, and SC Bodine
(2008) The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy related MuRF1gene. American Journal of Physiology: Endocrinology and Metabolism. 295:E785-797
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Schriks M, Roessig JM, Murk AJ, Furlow JD (2007) Thyroid hormone receptor isoform selectivity
of thyroid hormone disrupting compounds quantified with an in vitro reporter gene assay. Environmental Toxicology and Pharmacology 23:320-307.
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Weidner WJ, Waddell DS, Furlow JD. (2006) Measurement of the filtration coefficient (Kfc) in the lung
of Gallus domesticus and the effects of increased microvascular permeability. J Comp Physiol [B]
176(6):567-574
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Furlow, J.D. and E.S. Neff (2006) A developmental switch induced by thyroid hormone: Xenopus laevis metamorphosis. Trends in Endocrinolology and Metabolism 17:40-47.
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Schriks M, Zvinavashe E, Furlow JD, Murk AJ. (2006) Disruption of thyroid hormone-mediated Xenopus laevis tadpole tail tip regression by hexabromocyclododecane (HBCD) and 2,2',3,3',4,4',5,5',6-nonabrominated diphenyl ether (BDE206). Chemosphere. 65:1904-1908.
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Lim, W., Neff, E. S., and J. D. Furlow (2004) The mouse muscle creatine kinase promoter faithfully drives reporter gene expression in transgenic Xenopus laevis. Physiological Genomics. 18:79-86
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Furlow J. D., Yang, H. Y., Hsu, Y. M., Lim, W., Ermio, D. J., Chiellini, G., and T. S. Scanlan (2004) The thyroid hormone receptor agonist GC-1 preferentially induces tissue resorption in Xenopus laevis tadpoles. Journal of Biological Chemistry. 279:26555-26562
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Luria, A. and J. D. Furlow (2004) Spatiotemporal activation of retinoid-X receptors detected in live vertebrate embryos. Proceedings of the National Academy of Sciences. 101:8987-8992
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Lim, W, Nguyen, NH, Yang, HY, Scanlan, TS, and JD Furlow (2002) A thyroid hormone
antagonist that inhibits thyroid hormone action in vivo. Journal of Biological Chemistry 277:35664-35670
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Lim, W, and JD Furlow (2002) Ribozyme suppression of endogenous thyroid hormone receptor
activity in Xenopus laevis cells. Nucleic Acids Research 30:3490-3496
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Furlow, JD and A Kanamori (2002) The Transcription Factor Basic Transcription Element-Binding
Protein 1 is a Direct Thyroid Hormone Response Gene in the Frog Xenopus laevis. Endocrinology. 143:3295-3305
Furlow Lab, 274 Briggs Hall
Eric Neff, Cindy Chen, Monica Watson, Kari Pollock, Chris Craig-Veit
Endocrinology, developmental biology, molecular biology.
NPB
101
Systemic Physiology
Winter
NPB
128
Comparative Physiology: Endocrinology
Winter
NPB
152
Hormones and Behavior
Spring