Irwin H. Segel
Professor
ihsegel@ucdavis.edu


Office
247B Briggs Hall
(530) 752-3193


Picture of Irwin H. Segel
 
Degrees:
1962 PhD University of Wisconsin Biochemistry
1960 MS University of Wisconsin Biochemistry
1957 BS Rensselaer Polytechnic Institute, New York Chemistry
Research Interests:

Enzymology, physiology, and regulation of sulfur metabolism with emphasis on the enzymes of inorganic sulfate activation in fungi, plants, animals, and bacteria. Enzymes of thermophilic fungi


Graduate Groups not Housed in CBS:
Microbiology  
Publications:
  • MacRae I. J., Segel, I. H., and Fisher, A. J.. 2000. Crystal Structure of APS Kinase from Penicillium chrysogenum.. Biochemistry. 39:1613 - 1621
  • MacRae, I. J., Hanna, E., Ho, J. D., Fisher, A. J., and Segel, I. H. . 2000. Induction of positive cooperativity by amino acid replacements within the C-terminal domain of P. chrysogenum ATP sulfurylase.. Journal of Biological Chemistry. 275:36303-36310
  • MacRae, I., A. B. Rose, and Segel, I. H.. 1998. Adenosine 5'-Phosphosulfate (APS) Kinase from Penicllium chrysogenum: Site Directed Mutagenesis Studies on Putative Phosphoryl-Accepting and ATP P - Loop residues. . Journal of Biological Chemistry. 273:
Teaching Interests:
Bioenergetics and metabolic regulation. Enzyme kinetics and receptor-ligand interactions.