Sean H. Adams
Research Physiologist
sean.h.adams@arc.usda.gov


Office
WHNRC, 430 W. Health Sciences Dr., Rm. 212, Davis, CA 95616
530-754-4417



 
Degrees:
1994 PhD University of Illinois Nutritional Sciences
1991 MS UC, Santa Cruz Marine Sciences
1988 BA California State University, Fresno Biology
Department and Center Affiliations:
USDA-ARS Western Human Nutrition Research Center
Department of Nutrition
Professional Societies:
American Society for Nutrition (ASN)
American Physiological Society (APS)
North American Society for the Study of Obesity (NAASO)
CBS Graduate Group Affiliations:
Molecular, Cellular, and Integrative Physiology  
Graduate Groups not Housed in CBS:
Graduate Group in Nutrition (GGNB)  
Publications:
  • P.J. Oort, C.H. Warden, T.K. Baumann, T.A. Knotts, and S. H. Adams. Characterization of Tusc5, an adipocyte gene co-expressed in peripheral neurons. Mol. Cell. Endocrinology, 276(1-2):24-35, 2007
  • S. H. Adams, C. Lei, C.M. Jodka, S.E. Nikoulina, J.A. Hoyt, B. Gedulin, C.M. Mack, and E.S. Kendall. PYY[3-36] administration decreases the respiratory quotient and reduces adiposity in diet-induced obese mice. J. Nutrition, 136: 195-201, 2006
  • S.H. Adams, Wesley B. Won, S.E. Schonhoff, A.B. Leiter, and J.R. Paterniti, Jr. Effects of PYY[3-36] on short-term food intake in mice are not affected by prevailing plasma ghrelin levels. Endocrinology, 145:4967-4975, 2004
  • G. Perdomo, S.R. Cummerford, S.H. Adams, R.M. O'Doherty, and N.F. Brown. Increased Beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid induced insulin resistance despite intramyocellular lipid accumulation. J. Biol. Chem., 279(26):27177-27186, 2004
  • Fu, L., L. John, S.H. Adams, X.X. Yu, E. Tomlinson, M. Renz, P.M. Williams, R. Soriano, R. Corpuz, M. Moffat, R. Vandlen, L. Simmons, J. Foster, J-P. Stephan, S.P. Tsai, and T.A. Stewart. Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin deficient diabetes. Endocrinology, 145(6):2594-2603, 2004
  • Yu, X.X., D.A. Lewin, W. Forrest, & S.H. Adams. Cold elicits the simultaneous induction of fatty acid synthesis & beta-oxidation in rodent brown adipose tissue. Prediction from differential gene expression & confirmation in vivo. FASEB J.16: 155-168, 2002
  • Adams, S.H., C. Chui., S.L. Schilbach, X.X. Yu, A.D. Goddard, J.C. Grimaldi, J. Lee, P. Dowd, S. Colman, & D.A. Lewin. BFIT, a unique acyl-CoA thioesterase induced in thermogenic brown adipose tissue. Cloning, organization of the human gene, & assessment of a potential link to obesity. Biochem. J. 360: 135-142, 2001
  • Adams, S.H., G. Pan, & X.X. Yu. Perspectives on the biology of UCP homologues. Invited contribution for Biochem. Soc. Transactions 29(6): 798-802, 2001
  • Yu, X.X., D.A. Lewin, A. Zhong, J. Brush, P.W. Schow, S.W. Sherwood, G. Pan, & S.H. Adams. Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: contrast with the unique cold-induced mitochondrial carrier CGI-69. Biochem. J. 353: 369-375, 2001
  • Adams, S.H. Uncoupling protein homologs: emerging views of physiological function. Recent Advances in Nutritional Sciences, J. Nutr. 130: 711-714, 2000
  • Yu, X.X., J.L. Barger, B.B. Boyer, M.D. Brand, G. Pan, and S.H. Adams. Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, & mitochondrial proton leak kinetics. Am. J. Physiol. Endocrinol. Metab. 279: E433-E446, 2000
  • Yu, X.X., W. Mao, A. Zhong, P. Schow, J. Brush, S.W. Sherwood, S.H. Adams, and G. Pan. Characterization novel UCP5/BMCP1 isoforms and differential regulation of UCP4 and UCP5 expression through dietary or temperature manipulation. FASEB J. 14(11): 1611-1618, 2000
  • Mao, W., X.X. Yu, A. Zhong, W. Li, J. Brush, S.W. Sherwood, S.H. Adams, and G. Pan. UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells. FEBS Letters 443: 326-330, 1999
  • Adams, S.H., V. Esser, N.F. Brown, N.H. Ing, L . Johnson, D.W. Foster, and J.D. McGarry. Expression and possible role of muscle-type carnitine palmitoyltransferase I during sperm development in the rat. Biol. of Reprod. 59: 1399-1405, 1998
  • Adams, S.H. and J. Odle. Acetogenesis does not replace ketogenesis in fasting piglets infused with hexanoate. Am. J. Physiol. Endocrinol. Metab. 274: E963-E970, 1998
  • Adams, S.H., C. Sampaio Alho, G. Asins, F.G. Hegardt, and P.F. Marrero. Gene expression of mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in a poorly ketogenic mammal: effect of starvation during the neonatal period of the piglet. Biochem. J. 324: 65-73, 1997
  • Adams, S.H., X. Lin, X.X. Yu, J. Odle, and J.K. Drackley. Hepatic fatty acid metabolism in pigs and rats: major differences in endproducts, O2 uptake, and beta-oxidation. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 272: R1641-R1646, 1997
  • Lin, X., S.H. Adams, and J. Odle. Acetate represents a major product of heptanoate and octanoate beta-oxidation in hepatocytes isolated from neonatal piglets. Biochem. J. 318: 235-240, 1996
  • Ortiz, R.M., S.H. Adams, D.P. Costa, and C.L. Ortiz. Plasma vasopressin levels and water conservation in fasting, postweaned northern elephant seal pups (Mirounga angustirostris). Marine Mammal Sci. 12: 99-106, 1996
  • Odle, J., T.A.T.G. van Kempen, J.K. Drackley, and S.H. Adams. Carnitine palmitoyltransferase modulation of hepatic fatty acid metabolism and radio-HPLC evidence for low ketogenesis in neonatal pigs. J. Nutr. 125: 2541-2549, 1995
  • Tetrick, M.A., S.H. Adams, J. Odle, and N.J. Benevenga. Contribution of D-(-)-3-hydroxybutyrate to the energy expenditure of neonatal pigs. J. Nutr. 125: 264-272, 1995
  • Patterson-Buckendahl, P., S.H. Adams, R. Morales, W.S.S. Jee, C.E. Cann, and C.L. Ortiz. Skeletal development in newborn and weanling northern elephant seals. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 267: R726-R734, 1994
  • Adams, S.H. and J. Odle. Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 265: R761-R765, 1993
  • Adams, S.H. and D.P. Costa. Water conservation and protein metabolism in northern elephant seal pups during the postweaning fast. J. Comp. Physiol. B 163: 367-373, 1993
  • Adams, S.H., D.P. Costa, & S.C. Winter. Plasma carnitine in fasting neonatal and adult northern elephant seals. Am. J. Physiol. Endocrinol. Metab. 263: E570-E574, 1992
Laboratory Personnel:
WHNRC

Pieter J. Oort, Molecular Biologist; Trina A. Knotts, Ph.D., USDA Postdoctoral Fellow; Anthony P. Thomas, GGNB Ph.D. Student; Tamara N. Dunn, GGNB Ph.D. Student