Soichiro Yamada
Assistant Professor
syamada@ucdavis.edu
Biomedical Engineering (Grad)
Office
GBSF 2317
(530) 754-7251
Degrees:
2001
PhD
The Johns Hopkins University
Chemical Engineering
1996
BS
Rutgers University
Chemical Engineering
Research Interests:
Cell adhesion, traction force analysis, cadherin, cytoskeletal dynamics, 3D culture, live-cell imaging
Awards:
Hellman Family New Faculty Award, 2008
Beckman Young Investigator Award, 2009
CBS Graduate Group Affiliations:
Biochemistry, Molecular, Cellular and Developmental Biology
Specialties / Focus:
Biochemistry, Molecular, Cellular and Developmental Biology
Graduate Groups not Housed in CBS:
Biomedical Engineering
Publications:
Last updated 1/27/2011
Ounkomol C, Yamada S, Heinrich V. (2010) Single-cell adhesion tests against functionalized microspheres arrayed on AFM cantilevers confirm heterophilic E- and N-cadherin binding. Biophys J. 99(12):L100-2.
Nguyen TN, Uemura A, Shih W, Yamada S. (2010) Zyxin-mediated actin assembly is required for efficient wound closure. J Biol Chem. 285(46):35439-45.
Shih W, Yamada S. (2010) Myosin IIA dependent retrograde flow drives 3D cell migration. Biophys J. 98(8):L29-31.
Pokutta S, Drees F, Yamada S, Nelson WJ, Weis WI. (2008) Biochemical and structural analysis of alpha-catenin in cell-cell contacts. Biochem Soc Trans. 36(Pt 2):141-7
Yamada, S. and Nelson, W. J. Localized RhoA activation regulates actomyosin contraction and compaction of epithelial cell-cell adhesion (2007) J Cell Biol. 178:517-27
Yamada, S. and Nelson, W. J. Synapses: sites of cell recognition, adhesion, and functional specification. (2007) Annu Rev Biochem. 76:267-94
Reilein, A. Yamada, S. and Nelson, W. J. (2005) Self-organization of an acentrosomal microtubule network at the basal cortex of polarized epithelial cells J Cell Biol. 171:845
Drees, F. Pokutta, S. Yamada, S. Nelson, W. J. and Weis, W. I. (2005) Alpha-catenin is a molecular switch that binds E-cadherin/beta-catenin and regulates actin filament assembly. Cell 123:903
Yamada, S. Pokutta, S. Drees, F. Weis, W. I. and Nelson, W. J. (2005) Deconstructing the cadherin-catenin-actin complex. Cell 123:889
Nelson, W. J. Drees, F. and Yamada, S. (2005) Interaction of cadherin with the actin cytoskeleton. Novartis Found Symp. 269:159
Yamada, S. and Kuo, S. C. (2003) The inside story of Brownian motion: Revealing intracellular mechanics. Biophysics 43:180
Yamada, S. Wirtz, D. and Coulombe, P. A. (2003) The mechanical properties of simple epithelial keratins 8 and 18: discriminating between interfacial and bulk elasticities. J Struct Biol. 143:45-55.
Yamada, S. Wirtz, D. and Coulombe, P. A. (2002) Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Mol Biol Cell. 13:382-91.
Coulombe, P. A. Ma, L. Yamada, S. and Wawersik, M. (2001) Intermediate filaments at a glance. J Cell Sci. 114:4345-7
Bousquet, O. Ma, L. Yamada, S. Gu, C. Idei, T. Takahashi, K. Wirtz, D. and Coulombe, P. A. (2001) The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro. J Cell Biol. 155:747-54.
Ma, L. Yamada, S. Wirtz, D. and Coulombe, P. A. (2001) A 'hot-spot' mutation alters the mechanical properties of keratin filament networks. Nat Cell Biol. 3:503-6.
Coulombe, P. A. Bousquet, O. Ma, L. Yamada, S. and Wirtz, D. (2000) The 'ins' and 'outs' of intermediate filament organization. Trends Cell Biol. 10:420-8.
Yamada, S. Wirtz, D. and Kuo, S. C. (2000) Mechanics of living cells measured by laser tracking microrheology. Biophys J. 78:1736-47.
Courses:
BIM
020
Fundamentals of Bioengineering
Spring
BIM
102
Quantitative Cell Biology
Fall
BIM
202
Cell and Molecular Biology for Engineers
Winter
BIM
222
Cytoskeletal Mechanics
Fall