Jie Zheng
ASSOCIATE PROFESSOR
jzheng@ucdavis.edu

Physiology and Membrane Biology

Office
4145 Tupper Hall
530-752-1241


Picture of Jie Zheng
 
Degrees:
1998 PhD Yale University Physiology
1991 MS Beijing University Biophysics
1988 BS Beijing University Physiology and Biophysics
Awards:
University Scholarship, Yale University, 1992-1995
Guanghua Scholarship, Beijing University, 1988
Research Associate, Howard Hughes Medical Institute, 2000-2003
UCD Health System Research Award, 2008-2009
the Grass Foundation Travelling Scientist Award, 2009
Department and Center Affiliations:
Department of Physiology and Membrane Biology
Professional Societies:
Society for Neuroscience
Biophysical Society
Society of General Physiology
American Physiological Society
CBS Graduate Group Affiliations:
Molecular, Cellular, and Integrative Physiology  
Graduate Groups not Housed in CBS:
Pharmacology and Toxicology  
Publications: Last updated 10/8/2009
  • Praporski, S., S.M. Ng, A.D. Nguyen, C. Corbin, A. Mechler, J. Zheng, A. Conley, and L. Martin (2009) Organization of enzymes involved in sex steroid synthesis: protein-protein interactions in lipid membranes, Journal of Biological Chemistry, (in press)
  • Liang, S.-S., F. Yang, C. Zhou, Y. Wang, S. Li, C.K. Sun, J.L. Puglisi, D. Bers, C. Sun, and J. Zheng (2009) Temperature-dependent activation of neurons by continuous near-infrared laser, Cell Biochemistry and Biophysics, 53(1), 33-42
  • Qu, Z., W. Cheng, Y. Cui, Y. Cui, and J. Zheng (2009) Human disease-causing mutations disrupt an N-C terminal interaction and channel function of bestrophin 1, Journal of Biological Chemistry, 284:16473-16481
  • Sun, P., J. Wang, W. Gu, W. Cheng, G.-Z. Jin, E. Friedman, J. Zheng, and X. Zhen (2009) PSD-95 regulates D1 dopamine receptor resensitization, but not receptor-mediated Gs-protein activation, Cell Research, 19:612-624
  • Qiu, S., X.-M. Zhang, J.-Y. Cao, W. Yang, Y.-G. Yan, L. Shan, J. Zheng, and J.-H. Luo (2009) An ER retention signal located in the extracellular amino-terminal domain of NR2A subunit of NMDA receptors, Journal of Biological Chemistry, 284:20285-20298
  • Zheng, J., and K. Matulef (2008) Cyclic nucleotide-gated ion channels, In: Encyclopedia of Life Sciences (ELS), John Wiley & Sons, Ltd: Chichester.
  • Chen, T.Y., Y.F. Lin, and J. Zheng (2008) Electrophysiological measurements of membrane proteins, in Handbook on Biophysics, volume 1 Chapter 5
  • Vetter, I., W. Cheng, M. Peiris, B.D. Wyse, S.J. Roberts-Thomson, J. Zheng, G.R. Monteith, P.J. Cabot (2008) Rapid, opioid-sensitive mechanisms involved in transient receptor potential vanilloid 1 sensitization, Journal of Biological Chemistry, 283, 19540-19550
  • Zheng, J., and K. Matulef (2009) Cyclic nucleotide-gated ion channels, In: Encyclopedia of Life Sciences (ELS), John Wiley & Sons, Ltd: Chichester.
  • Zheng, J. (2009) FRET and its biological application as a molecular ruler, in Handbook of Modern Biophysics, Vol. 3: Biomedical Applications in Biophysics, Humana Press, (in press)
  • Ying, G., S.S. Liu, S. Qiu, W. Cheng, J. Zheng, J.H. Luo (2007) Fluorescence resonance energy transfer analysis of subunit assembly of the ASIC channel, Biochemical and Biophysical Research Communications, 359, 143-150
  • Cheng, W., F. Yang, C.L. Takanishi, and J. Zheng (2007) Thermosensitive TRPV Channel Subunits Co-assemble into Heteromeric Channels with Intermediate Conductance and Gating Properties, Journal of General Physiology, 129, 191-207 ** featured on the cover **
  • Bykova, E.A. and J. Zheng (2009) Spectra FRET, a fluorescence resonance energy transfer method in live cells, Annual Reviews in Fluorescence 2007, Chapter 4, Springer, (in press)
  • Zheng, J. (2008) Patch fluorometry, In: Encyclopedia of Life Sciences (ELS), John Wiley & Sons, Ltd: Chichester.
  • Bykova, E.A., X.D. Zhang, T.Y. Chen, and J. Zheng (2006) Large movement in the C terminus of CLC-0 chloride channel during slow gating, Nature Structural and Molecular Biology, 13, 1115-1119
  • Christina L. Takanishi, Ekaterina A. Bykova, Wei Cheng, and Jie Zheng (2006) Quantification of GFP-based FRET in transfected cells, Brain Research, 1091(1), 132-139
  • Jie Zheng (2006) Patch fluorometry: shedding new light on ion channels, Physiology, 21, 6-12
  • Jie Zheng (2006) Spectroscopy-based quantitative fluorescence resonance energy transfer analysis, Methods in Molecular Biology, 337, 65-78
  • Jie Zheng, and William N. Zagotta (2004) Stoichiometry and assembly of olfactory cyclic nucleotide-gated channels, Neuron, 42, 411-421
  • Zheng, J., and W.N. Zagotta (2003) Patch-clamp fluorometry recording of conformational rearrangements of ion channels, Science's STKE, pl7
  • Zheng, J., M.D. Varnum, and W.N. Zagotta (2003) Disruption of an intersubunit interaction underlies Ca2+-calmodulin modulation of cyclic nucleotide-gated channels, Journal of Neuroscience, 23(22), 8167-8175
  • Zheng, J., M.C. Trudeau, and W.N. Zagotta (2002) Rod cyclic nucleotide-gated channels have a stoichiometry of three CNGA1 subunits and one CNGB1 subunit, Neuron, 36, 891-896 ** Commentary in Nature Review Neuroscience and in Neuron **
  • Zheng, J., L. Venkataramanan, and F.J. Sigworth (2001) Hidden Markov model analysis of intermediate gating steps associated with the pore gate of Shaker potassium channels, Journal of General Physiology, 118, 547-562
  • Zheng, J., and W.N. Zagotta (2000) Gating rearrangements in cyclic nucleotide-gated channels revealed by patch-clamp fluorometry, Neuron, 28, 369-374
  • Zheng, J., and F.J. Sigworth (1998) Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels, Journal of General Physiology, 112, 457-474
  • Zheng, J., and F.J. Sigworth (1997) Selectivity changes during activation of mutant Shaker potassium channels, Journal of General Physiology, 110, 101-117 ** featured on the cover **
  • Mathur, R., J. Zheng, Y. Yan, and F.J. Sigworth (1997) Role of the S3-S4 linker in Shaker potassium channel activation, Journal of General Physiology, 109, 191-200
  • Zhang, R.J., D.J. Zou, and J. Zheng (1995) Correlation of receptive field position of mechanosensory neurons and the strength of their connections to AP neurons in the CNS of the leech (Whitmania pigra), Invertebrate Neuroscience, 1, 249-254
  • Zhang, R.J., D.J. Zou, J. Zheng, and W.H. Xiong (1992) Positional discrimination of the AP neuron synapses in the leech Whitmania pigra, Science in China, Series B, 12, 1287-1294
  • Liu, K.Q., J. Zheng, Y.Q. Lu, Y.H. Zhang, and F. Liu (1991) Automatic analysis of single-channel records, Acta Biophysica Sinica, 7(3), 346-351
Laboratory Personnel:
Current Member:

Katya Bykova, Wei Cheng, Fan Yang

Previous lab members:

Chris Takanishi (currently a graduate student at CDB graduate group)

Courses:
MCP 210A Advanced Physiology Fall
HPH 400 Physiology Fall
PTX 202 Principles of Pharmacology and Toxicology Winter