Helen Raybould
Professor
heraybould@ucdavis.edu
Office
2153 Haring Hall
1986
PhD
University of Liverpool, United Kingdom
Physiology
1977
BS
University of Birmingham, United Kingdom
Biological Sciences
Neural innervation of the gastrointestinal tract, in particular the primary afferent innervation.
Janssen Award for Basic Research In Digestive Sciences, 2000
Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine
American Physiological Society, American Gastroenterology Association
Molecular, Cellular, and Integrative Physiology
Nutrition
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Raybould, H.E., D. Bohan, N Darcel, S.L. Freeman. Luminal glucose sensing in the rat intestine has characteristics of a sodium-glucose cotransporter. Am J Physiol Gastrointest Liver Physiol. 291(3):G439-45 (2006).
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Nelson, D.W., J.W. Sharp, M. Brownfield, H.E. Raybould and D.M. Ney. Localization and activation of GLP-2 receptors on vagal afferents in the rat. Endocrinology 148: 1954-1963 (2007).
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Whited, K.L.,D. Thao, K.C.K. Lloyd, A.S. Kopin, and H.E. Raybould. Targeted disruption of the murine CCK-1 receptor gene reduces intestinal lipid-induced feedback inhibition of gastric function. Am J Physiol Gastrointest Liver Physiol. 291(1):G156-62 (2006).
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Glatzle, J., Wang, Y., Adelson, D., Kalogeris, T.J., Zittel, T.T., Tso, P., Wei, J.Y., and Raybould, H.E. Chylomicron components activate duodenal vagal afferents via a cholecystokinin A receptor-mediated pathway to inhibit gastric motor function in the rat. J Physiol (London) 550: 657-664 (2003).
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Freeman, S.L., Glatzle, J., Robin, C.S., Valdellon, M., Sternini, C., Sharp, J.W.and Raybould,H.E. Ligand-induced 5-HT3 receptor internalization in enteric neurons in rat ileum. Gastroenterology 131(1):97-107 (2006).
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Darcel, N., A. Liou, D, Tomé, H.E. Raybould. Activation of vagal afferents in the rat duodenum by protein digests requires PepT1. J. Nutr.; 135:1491-5 (2005).
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Whited, K.L., Lu, D., Tso, P., Lloyd, K.C.K. and Raybould, H.E. Apolipoprotein A-IV is required for physiological responsiveness to lipid in the mouse intestine. J Physiol. 569: 949-958 (2005).
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Patierno, S., H.E. Raybould, C. Sternini. Abdominal surgery induces mu opioid receptor endocytosis in enteric neurons of the guinea pig ileum. Neuroscience 123(1):101-9. (2004).
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Glatzle J, Darcel N, Rechs AJ, Kalogeris TJ, Tso P, Raybould HE. Apolipoprotein AIV inhibits gastric motility via a capsaicin-sensitive and CCK-A receptor pathway in rats. Am J Physiol. Reg. Integ. Comp. 287(2):R354-9 (2004).
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Glatzle,J., C. Sternini, C. Robin, T.T. Zittel, H. Wong, J.R. Reeve Jr, and H.E. Raybould. Expression of 5-HT3 receptors in the rat gastrointestinal tract. Gastroenterology 123: 217-226 (2002).
Integrative gastrointestinal physiology