Robert H Weiss
Professor
rhweiss@ucdavis.edu
Nephrology (Internal Med)
Chief of Nephrology, Sacramento VA Medical Center
Office
GBSF rm 6312
(530) 752-4010
Degrees:
1991
University of California, San Francisco
Fellowship, Nephrology
1984
MD
University of California, Irvine
Medicine
1980
MS
University of California, Los Angeles
Medical Physics
1978
MS
University of California, Los Angeles
Physical Chemistry
1976
BA
University of California, Santa Cruz
Chemistry
Research Interests:
cyclins and cyclin inhibitors, cancer growth control, metabolomics and proteomics, polycystic kidney disease
Department and Center Affiliations:
UC Davis Cancer Center
CBS Graduate Group Affiliations:
Molecular, Cellular, and Integrative Physiology
Graduate Groups not Housed in CBS:
Immunology
Comparative Pathology
Comparative Pathology
Publications:
Last updated 5/21/2010
Weiss RH, Joo A and CJ Randour. 2000. p21Waf1/Cip1 is an assembly factor required for PDGF-induced vascular smooth muscle cell proliferation. Journal of Biological Chemistry. 275:10285-10290
Davis BB, Thompson DA, Howard LL, Morisseau C, Hammock BD and
RH Weiss. 2002. Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. Proceedings of the National Academy of Sciences (USA). 99(4):2222-2227
Lin, P.Y., Fosmire, S.P., Baksh, S., Modiano, J.F., Weiss, R.H. Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance, Molecular Cancer, 6:16, 2007
Park, S.H., Park, J.Y., Weiss, R.H. Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA-damaging chemotherapy associated with enhancement of phospho-p53, Journal of Urology 180(1):352-60, 2008
Park, S.H., Wang, X., Liu, R., Lam, K.S., Weiss, R.H. High throughput screening of a small molecule one-bead-one-compound combinatorial library to identify attenuators of p21 as chemotherapy sensitizers, Cancer Biology & Therapy, 7(12), 2015-22, 2008
Kim, K.M., Aronov, P.A., Zakharkin, S.O., Anderson, D., Perroud, B., Weiss, R.H., Urine metabolomic analysis for kidney cancer detection and biomarker discovery, Molecular and Cellular Proteomics, 8(3):558-70, 2009
Perroud, B., Ishimaru, T., Borowsky, A.D., Weiss, R.H. Grade-dependent proteomic characterization of kidney cancer, Molecular and Cellular Proteomics, May;8(5):971-85, 2009
Liu , J.-Y. Park, S.-H., Morisseau , C., Hwang , S. H., Hammock, B., Weiss, R.H., Sorafenib Has sEH Inhibitory Activity Which Contributes to Its Effect Profile in vivo, Molecular Cancer Therapeutics, 2009 Aug;8(8):2193-203, 2009
Taylor, S.L., Ganti, S., Bukanov N.O., Chapman, A., Fiehn, O., Osier, M., Kim, K., Weiss, R.H. A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease, American Journal of Physiology: Renal Physiology, in press, 2010
Weiss, R.H. p21Waf1/Cip1 as a therapeutic target in breast and other cancers, Cancer Cell, 4: 426-429, 2003