Peter Michael Cala
Professor and Chair Physiology and Membrane Biology
pmcala@ucdavis.edu

Human Physiology-Medicine

Office
4136 Tupper Hall
752-1285


Picture of Peter Cala
 
Degrees:
1974 PhD Case Western Reserve University Physiology
1970 BA Case Western Reserve University Biology/Chemistry
Research Interests:

Sodium-Proton exchange (NHE1), Structure-Function, cell volume and pH regulation, Ion transport
Awards:
1994-2004 NIH MERIT award
1999 Research Mentor Award: UCDMC
2000 Leader of the Membrane Biology Initiative, UCDSOM
2003-2005 Association of Chairs of Physiology Departments: President
Professional Societies:
Americam Physiological Society
Association of Chairs of Physiology Departments (ACDP: past president)
CBS Graduate Group Affiliations:
Molecular, Cellular, and Integrative Physiology  
Publications:
  • 2003 Stine F. Pedersen, Scott A. King, Robert R. Rigor, Zhenpeng Zhuang, Jaimie M. Warren, and Peter M. Cala. Molecular cloning of NHE1 from winter flounder RBCs: activation by osmotic shrinkage, cAMP, and calyculin A. Am J Physiol Cell Physiol 284: C1561-C1576.
  • 2004 Pedersen, S.F., Cala, P.M. Comparative biology of the ubiquitous Na+/H+ exchanger, NHE1; lessons from erythrocytes. J. Exp. Zoolog. Part A Comp. Exp. Biol. 2004 Jul 1; 301(7):569-78.
  • 2005 Anderson, S.E., D. M. Kirkland, A. Beyschau, and P.M. Cala. Acute effects of 17ß-estradiol on pH, Na, and Ca and ischemia/reperfusion injury. Am J. Physiol: Cell Physiol. 288: C57-C64.
  • 2006 Pedersen, S.F., M.E. O’Donnell, S.E. Anderson and P.M. Cala. Physiology and pathophysiology of Na+/H+ exchange and Na+-K+-2Cl- cotransport in the heart, brain and blood. Am. J. Physiol. Regul. Integr. Comp. Physiol. 291: R1-R25.
  • 2006 Holt, M.E., S.A. King, P.M. Cala and S.E. Pedersen. Regulation of the Pleuronectes americanus Na+/H+ exchanger by osmotic shrinkage, beta-adrenergic stimuli, and inhibition of the Ser/Thre protein phosphatases. Cell. Biochem. Biophys. 45: 1-18.
  • 2007 King, S. A., E.B. Nygaard , R.R. Rigor R.R, S. F. Pedersen, and P. M. Cala. NHE1 inhibition by amiloride- and benzoyl guanidine-type compounds: inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity. J Biol Chem. 282(27): 19716-27. Epub 2007 May 10.
  • 2008 Ortiz-Acevedo A, Rigor III RR, Maldonado HM, Cala PM. Activation of Na +/H+ and K+/H+ Exchange by Calyculin A in Amphiuma tridactylum Red Blood Cells; implications for the control of volume-induced ion flux activity. Am J Physiol Cell Physiol, 284: C-1123-32.
Teaching Interests:
Membrane transport theory. Electroneutral and conductive transport.
Courses:
Med HP400 Medical Physiology Winter
PGG 210A General/Membrane Physiology Fall