Tsung-Yu Chen
Professor
tycchen@ucdavis.edu

Neurology - Medicine

Office
(530) 754-7166


Picture of Tsung-Yu Chen
 
Degrees:
1994 PhD Johns Hopkins University School of Medicine
1988 MS National Yang-Ming Medical College
1986 MD National Yang-Ming Medical College
Research Interests:

Structures, functions and physiological roles of ion channels.
Awards:
Paul Cranefield Award, Society of General Physiologists, 2004.
Department and Center Affiliations:
Center for Neuroscience and Dept of Neurology
Professional Societies:
Biophysical Society, USA
Society of General Physiologists, USA
CBS Graduate Group Affiliations:
Biochemistry, Molecular, Cellular and Developmental Biology  
Neuroscience  
Biophysics  
Molecular, Cellular, and Integrative Physiology  
Publications: Last updated 11/20/2009
  • Chen T.-Y. (2005) Structure and function of ClC channels. Ann. Rev. Physiol. 67: 809-839.
  • Li Y, Yu W,-P., Lin C.-W. and Chen T.-Y. (2005) Oxidation and Reduction Control of the Inactivation Gating of Torpedo ClC-0 Chloride Channels. Biophys J. 88(6):3936-45.
  • Bykova E. A., Zhang X.-D., Chen T.-Y., and Zheng J. (2006) Large movement in the C-terminus of CLC-0 chloride channel during slow gating. Nature Struct & Mol. Biol. 13: 1115-1119.
  • Tseng P.-Y., Bennetts B., and Chen T.-Y. (2007) Cytoplasmic ATP inhibition of CLC-1 is enhanced by low pH. J. Gen. Physiol. 130: 217-221.
  • Chen T.-Y., and Hwang, T.-C. (2008) CLC-0 and CFTR: Chloride channels evolved from transporters. Physiol. Rev. 88: 351-387.
  • Zhang X.-D., Tseng P.-Y., Yu W.-P., and Chen T.-Y. (2009) Blocking pore-open mutants of CLC-0 by amphiphilic blockers. J. Gen. Physiol. 133: 43-58.
  • Zhang X.-D., and Chen T.-Y. (2009) Amphiphilic blockers punch through a mutant CLC-0 pore. J. Gen. Physiol. 133: 59-68.
Laboratory Personnel:
Chen Lab

Pang-Yen Tseng, Wei-Ping Yu, Xiao-Dong Zhang

Courses:
NSC 221 Cellular Neuroscience Fall