Richard Michelmore

image of Richard Michelmore

Professor and Director

Departments

Molecular & Cellular Biology
Microbiology - Medicine
Plant Sciences
UC Davis Genome Center

Offices and Labs

4311 GBSF
530-752-1729
Assistant: Chris Colbert
530-752-7598
cmcolbert@ucdavis.edu

Profile Introduction

Genetics and genomics of plant-pathogen interactions.

Degrees

1979 PhD Natural Sciences University of Cambridge, UK
1976 BA Natural Sciences University of Cambridge, UK

Research Contribution

Developing and implementing genetic solutions to pest and disease problems in plants that result in higher quality foods produced with reduced chemical inputs. Development of genomic approaches for the efficient utilization of genetic information. Strategies for resistance gene deployment to enhance durability of disease resistance and stability of the global food supply.

Research Interests

Genetics and genomics of disease resistance in plants

Please see website for details

Awards

Fellow, American Association for the Advancement of Science
Novozymes Inc. Endowed Chair in Genomics

Department and Center Affiliations

UC Davis Genome Center
Department of Molecular & Cellular Biology, CBS
Department of Medical Microbiology & Immunology, SOM
Department of Plant Sciences, CA&ES

ProfessionalSocieties

American Association for the Advancement of Science
American Phytopathological Society
American Society of Plant Biologists
Genetics Society of America

CBS Grad Group Affiliations

Plant Biology
Integrated Genetics and Genomics

Specialties / Focus

Plant Biology
  • Molecular Biology, Biochemistry, and Genomics
Integrated Genetics and Genomics
  • Model Plants
  • Plant Breeding
  • Integrated Genetics and Genomics

Graduate Groups not Housed in CBS

Plant Pathology
Agronomy and Horticulture

Labs

The Genome Center website
  • Please see http://michelmorelab.ucdavis.edu

Teaching Interests

Biotechnology and genetics of crop improvement. Impact of biotechnology on society. Genomics

Publications

7/22/2015 1:34:38 PM
  • Meyers, B.C., Kozik, A., Griego, A., Kuang, H. and Michelmore, R.W. (2003). Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis. Plant Cell 15:809-834.
  • Kuang, H., Woo, S.-S., Meyers, B., Nevo, E. and Michelmore, R.W. (2004). Multiple genetic processes result in heterogeneous rates of evolution within the major cluster of disease resistance genes in lettuce. Plant Cell 16:2870-2894.
  • Bernal, A., Pan, Q., Pollack, J., Rose, L., Willets, N., Kozik, A., Michelmore, R. (2005). Functional dissection of the Pto resistance gene using DNA shuffling. J. Biol. Chem. 280:23073-83.
  • McHale, L., Tan, X., Koehl, P., Michelmore, R.W. (2006). Plant NBS-LRR proteins: adaptable guards. Genome Biology 7:212.
  • West, M. A.L., van Leeuwen, H., Kozik, A., Kliebenstein, D. J., Doerge, R. W., St.Clair, D. A., Michelmore, R.W. (2006). High-density haplotyping with microarray-based expression and single feature polymorphism markers in Arabidopsis. Genome Research 16: 702-712.
  • West, M.A.L., Kim, K., Kliebenstein, D., van Leeuwen, H., Michelmore, R.W., Doerge, R.W., St Clair, D.A. (2007). Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in Arabidopsis. Genetics 175:1441-50.
  • Truco, M.J., Antonise, R., Lavelle, D., Ochoa, O., Kozik, A, Witsenboer, H., Fort, S., Jeuken, M.J.W., Kesseli, R. V., Lindhout, P., Michelmore, R.W., Peleman, J. (2007). A high-density, integrated genetic linkage map of lettuce (Lactuca spp.). Theor. Appl. Genet. 115:735-746.
  • Wroblewski, T., Piskurewicz, U., Tomczak, A., Ochoa, O., & Michelmore, R.W. (2007). Multiple resistance specificities are lost due to silencing homologs of the RGC2 NBS-LRR-encoding gene family in lettuce. Plant J. 51:803-818.
  • Caldwell, K.S. & Michelmore, R.W. (2009). Genes encoding defense signaling proteins in plants are more conserved than those encoding recognition proteins. Genetics 181:671-84.
  • Wroblewski, T., Caldwell, K.S., Piskurewicz, U., Cavanaugh, K.A., Xu, H., Kozik, A., Ochoa, O., McHale, L.K., Lahre, K., Jelenska, J., Castillo, J.A., Vinatzer, B.A., Greenberg, J.T., Michelmore, R.W. (2009). Large-scale analysis of interactions between several crop species and the effector repertoires from multiple Pseudomonas and Ralstonia spp. Plant Physiology 150:1733-49.
  • Luo, Y., Caldwell, K., T. Wroblewski, Wright, M.E., & Michelmore, R.W. (2009). Cleavage of a negative regulator of plant innate immunity, RIN4, is dependent on resistance genes and affected by multiple bacterial effectors. The Plant Cell 21:2458-2472.
  • Cantu, D., Vanzetti, L.S., Sumner, A., Dubcovsky, M., Matvienko, M., Distelfeld, A., Michelmore, R., Dubcovsky, J. (2010). Small RNAs, DNA methylation and transposable elements in wheat. BMC Genomics 11: 408.
  • Cantu, D., Govindarajulu, M., Kozik, A., Wang, M., Chen, X., Michelmore, R.W., Dubcovsky, J. (2011). Next-generation sequencing provides rapid access to the genes of wheat stripe rust. Plos One 6:e24230.
  • Michelmore, R.W., Christopoulou, M., Caldwell. K. (2013). Impacts of resistance gene genetics, function, and evolution on a durable future. Ann. Rev. Phytopathol. 51: 291–319.
  • Matvienko, M., Kozik, A., Froenicke, L., Lavelle, D., Martineau, B., Perroud, B., Michelmore, R. (2013). Consequences of normalizing transcriptomic and genomic libraries of plant genomes using a duplex-specific nuclease and tetramethylammonium chloride. PLoS One. 8:e55913.
  • Truco, M.J., Ashrafi, H., Kozik, A., van Leeuwen, H., Bowers, J., Reyes Chin Wo, S., Stoffel, K., Xu, H., Hill, T., van Deynze, A., Michelmore, R.W. (2013). An ultra high-density, transcript-based, genetic map of lettuce. G3, Genes, Genomes, Genetics. 3:617-631
  • Wei, Z., Julkowska, M.M., Laloë, J.-O., Hartman, Y.,  de Boer, G.-J., Michelmore, R.W., van Tienderen, P., Testerink, C.S., Schranz, M.E.  (2014).  A mixed model QTL analysis for salt tolerance in crop-wild hybrids of lettuce seedlings.  Mol. Breeding 34:1389-1400.

  • Govindarajulu, M., Epstein, L., Wroblewski, T., & Michelmore, R.W. (2014). Host-induced gene silencing inhibits the biotrophic pathogen causing downy mildew of lettuce.  Pl. Biotech. J. DOI: 10.1111/pbi.1230.

  • Wroblewski, T., Matvienko, M., Piskurewicz, U., Xu, H., Martineau, B., Wong, J., Kozik, A., Michelmore, R. (2014).  Distinctive profiles of small RNA couple inverted repeat-induced posttranscriptional gene silencing with endogenous RNA silencing pathways in Arabidopsis.  RNA 20:1987 – 1999.

  • Derevnina and Michelmore (2015).  Wheat rusts never sleep but neither do sequencers: will pathogenomics transform the way plant diseases are managed?  Genome Biology 16:44-47. DOI 10.1186/s13059-015-0615-3.

  • Derevnina, L., Chin-Wo-Reyes, S., Martin, F., Wood, K., Froenicke, L., Spring, O., Michelmore, R. (2015).  Genome sequence and architecture of the tobacco downy mildew pathogen, Peronospora tabacina. Mol. Pl. Microbe Interact. In press.

  • Christopoulou, M., McHale, L.K., Kozik, A., Reyes-Chin Wo, S., Wroblewski, T., Michelmore, R.W. (2015).  Dissection of two complex clusters of resistance genes in lettuce (Lactuca sativa).  Molec. Pl.-Micobe Interact.  http://dx.doi.org/10.1094/MPMI-06-14-0175-R.

  • Please see website for additional publications.