Carol A. Erickson
Distinguished Professor Emerita
Molecular & Cellular Biology
Offices and Labs
3133 Life Sciences Addition
|1976||PhD||Cell Biology||Yale University|
|1971||BA||Biology||Wilson College, Pennsylvania|
Our research focuses on the development of the avian trunk neural crest. We are particularly interested in the mechanisms that segregate the neural crest lineage from the neural epithelium, the mechanisms that guide specific neural crest lineages along different migratory pathways, and the control of neural crest cell differentiation. The laboratory uses a number of experimental approaches to address cellular and molecular aspects of neural crest development including: surgical manipulation, cell culture, in vitro embryo culture, in ovo electroporation of expression plasmids, and gene knockdown using antisense oligonucleotides and morpholinos.
Phi Beta Kappa, 1971
Research Career Development Award (NIH), 1983-1988
Elected Fellow, AAAS, 2001
Department and Center Affiliations
Molecular and Cellular Biology
Society for Developmental Biology
Society for Cell Biology
American Society for the Advancement of Science
Specialties / Focus
Biochemistry, Molecular, Cellular and Developmental Biology
- Differentiation, Morphogenesis and Wound Healing
Graduate Groups not Housed in CBS
Phil Spear, Jose Vilches-Moure
Cell Biology, Developmental Biology
MCB 258 Seminar in Development (Winter)
MCB 259 Literature in Developmental Biology (Fall,Winter,Spring)
MCB 145 Cell Signaling (Spring)
MCB 213 Core Course in Developmental Biology (Winter)
1/19/2012 12:20:17 PM
Kos, R, MV Reedy, RL Johnson and CA Erickson. 2001. The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. Development 128:1467-1479
Santiago A and CA Erickson. 2002. Ephrin-B ligands play a dual role in the control of neural crest cell migration. Development 129:3621-3632
Kos, R, RP Tucker, R Hall, T Duong, and CA Erickson. 2003. Methods for Introducing Morpholinos into the Chicken Embryo. Developmental Dynamics 226: 470-477
Delalande, J.M., Barlow, A.J., Thomas, A.J., Wallace, A.S., Thapar, N., Erickson, C.A., Burns, A.J., 2007. The receptor tyrosine kinase RET regulates hindgut colonization by sacral neural crest cells. Dev. Biol. 313:279.
Harris, M.L., Erickson, C.A., 2007. Lineage specification in neural crest cell pathfinding. Dev. Dyn. 236, 1-19.
Harris,M.L., Hall,R., and Erickson,C.A. (2008). Directing pathfinding along the dorsolateral path - the role of EDNRB2 and EphB2 in overcoming inhibition. Development 135, 4113- 4122.
Thomas,A.J. and Erickson,C.A. (2009). FOXD3 regulates the lineage switch between neural crest-derived glial cells and pigment cells by repressing MITF through a non-canonical mechanism. Development 136, 1849-1858.
Ahlstrom,J.D. and Erickson,C.A. (2009). The neural crest epithelial-mesenchymal transition in 4D: a ‘tail’ of multiple non-obligatory cellular mechanisms. Development 136, 1801-1812.
Kuo, B.R. and Erickson, C.A. (2011) Vagal neural crest cell migratory behavior: a transition between the cranial and trunk crest. Dev. Dyn. 240, 2084-100.