Carol A. Erickson

image of Carol A. Erickson

Distinguished Professor Emerita

Departments

Molecular & Cellular Biology

Offices and Labs

3133 Life Sciences Addition
752-8318

Degrees

1976 PhD Cell Biology Yale University
1971 BA Biology Wilson College, Pennsylvania

Research Interests

Our research focuses on the development of the avian trunk neural crest. We are particularly interested in the mechanisms that segregate the neural crest lineage from the neural epithelium, the mechanisms that guide specific neural crest lineages along different migratory pathways, and the control of neural crest cell differentiation. The laboratory uses a number of experimental approaches to address cellular and molecular aspects of neural crest development including: surgical manipulation, cell culture, in vitro embryo culture, in ovo electroporation of expression plasmids, and gene knockdown using antisense oligonucleotides and morpholinos.

Awards

Phi Beta Kappa, 1971
Research Career Development Award (NIH), 1983-1988
Elected Fellow, AAAS, 2001

Department and Center Affiliations

Molecular and Cellular Biology

ProfessionalSocieties

Society for Developmental Biology
Society for Cell Biology
American Society for the Advancement of Science

Specialties / Focus

Biochemistry, Molecular, Cellular and Developmental Biology
  • Differentiation, Morphogenesis and Wound Healing
  • Development
  • Signal Transduction and Gene Regulation

Graduate Groups not Housed in CBS

Comparative Pathology

Publications

1/19/2012 12:20:17 PM
  • Kos, R, MV Reedy, RL Johnson and CA Erickson. 2001. The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. Development 128:1467-1479
  • Santiago A and CA Erickson. 2002. Ephrin-B ligands play a dual role in the control of neural crest cell migration. Development 129:3621-3632
  • Kos, R, RP Tucker, R Hall, T Duong, and CA Erickson. 2003. Methods for Introducing Morpholinos into the Chicken Embryo. Developmental Dynamics 226: 470-477
  • Delalande, J.M., Barlow, A.J., Thomas, A.J., Wallace, A.S., Thapar, N., Erickson, C.A., Burns, A.J., 2007. The receptor tyrosine kinase RET regulates hindgut colonization by sacral neural crest cells. Dev. Biol. 313:279.
  • Harris, M.L., Erickson, C.A., 2007. Lineage specification in neural crest cell pathfinding. Dev. Dyn. 236, 1-19.
  • Harris,M.L., Hall,R., and Erickson,C.A. (2008). Directing pathfinding along the dorsolateral path - the role of EDNRB2 and EphB2 in overcoming inhibition. Development 135, 4113- 4122.
  • Thomas,A.J. and Erickson,C.A. (2009). FOXD3 regulates the lineage switch between neural crest-derived glial cells and pigment cells by repressing MITF through a non-canonical mechanism. Development 136, 1849-1858.
  • Ahlstrom,J.D. and Erickson,C.A. (2009). The neural crest epithelial-mesenchymal transition in 4D: a ‘tail’ of multiple non-obligatory cellular mechanisms. Development 136, 1801-1812.
  • Kuo, B.R. and Erickson, C.A. (2011) Vagal neural crest cell migratory behavior: a transition between the cranial and trunk crest. Dev. Dyn. 240, 2084-100.

Labs

Erickson
  • Phil Spear, Jose Vilches-Moure

Teaching Interests

Cell Biology, Developmental Biology

Courses

MCB 258 Seminar in Development (Winter)
MCB 259 Literature in Developmental Biology (Fall,Winter,Spring)
MCB 145 Cell Signaling (Spring)
MCB 213 Core Course in Developmental Biology (Winter)