James S. Clegg

Professor Emeritus

Departments

Molecular & Cellular Biology

Offices and Labs

Bodega Marine Laboratory
(707) 875-2010

Degrees

1961 PhD Biology The Johns Hopkins University
1958 BS Zoology Pennsylvania State University

Research Interests

Biochemical and biophysical adaptations in marine invertebrates; intracellular organization of "soluble" enzymes and other macromolecules not strongly bound to cell ultrastructure; stress proteins and molecular chaperones, primarily in invertebrates.

Awards

Fulbright Senior Research Fellow, University of London, UK, and Ghent University, Belgium
Fellow of the AAAS
Phi Beta Kappa
Woodrow Wilson Fellow

Department and Center Affiliations

Section of Molecular and Cellular Biology

ProfessionalSocieties

Biophysical Society; AAAS; American Society for Cell Biology; Soc. Integr. Compar. Biol. (Comp. Biochem. Physiol.); Soc. Cryobiology; Cell Stress Society International

Specialties / Focus

Biochemistry, Molecular, Cellular and Developmental Biology
  • Cellular Responses to Toxins and Stress

Teaching Interests

Physiological and biochemical adaptations of marine organisms; the heat shock (stress) response and stress proteins in invertebrates; organization and properties of eukaryotic cell cytoplasm

Courses

NPB 141 Physiological Adaptations of Marine Organisms (Spring)
NPB 141P Advanced Laboratory Topics (Spring)

Publications

5/21/2010 9:26:34 AM
  • Warner, A.H., R.T. Brunet, T.H. MacRae and J.S. Clegg. 2004. Artemin is an RNA- binding protein with high thermal stability and potential RNA chaperone activity. Arch. Biochem. Biophys. 424:189-200.
  • Qiu, Z., R.I. Viner, T.H. MacRae, J.K. Willsie and J.S. Clegg. 2004. A small heat shock protein from Artemia franciscana is phosphorylated at serine 50. Biochim. Biophys. Acta 1700:75-83.
  • Collins, C.H. and J.S. Clegg. 2004. A small heat shock protein, p26, from the crustacean Artemia protects mammalian cells (Cos-1) against oxidative damage. Cell Biol. Intern. 28:449-455.
  • Chen T, R Amons, JS Clegg, AH Warner and TH MacRae. 2003. Molecular characterization of artemin and ferritin from Artemia franciscana. European Journal of Biochemistry 270:137-145.
  • Willsie JK and JS Clegg. 2002 Small heat shock protein p26 associates with nuclear lamins and HSP 70 in nuclei and nuclear matrix fractions from stressed cells. Journal of Cellular Biochemistry 84:601-614.