Barbara Horwitz

image of Barbara Horwitz

Distinguished Professor

Departments

Physiology & Membrane Biology
Neurobiology, Physiology and Behavior

Offices and Labs

280A Briggs Hall
(530) 752-0169
280 Briggs Hall

Profile Introduction

Genetic, neural, and hormonal regulation of energy balance; alterations with obesity/age; current research focuses on mechanisms utilized by mammalian hibernators that result in CNS neuroprotection and survival in extreme environments.

Degrees

BS (Zoology) University of Florida
MS (Zoology) University of Florida
PhD (Physiology) Emory University

Research Interests

Extracellular signal reception/intracellular signal transduction and uncoupling proteins; physiological changes with obesity/aging; mechanisms of neuroprotection

Awards

Academic Senate Distinguished Teaching Award
Fellow AAAS
UC Davis Prize for Teaching & Scholarly Achievement
UC Presidential Award for Excellence in Fostering Undergraduate Research
NIH-NIA MERIT Award
Arthur C. Guyton Physiology Teacher of the year (American Physiological Society)
President of the Society of Experimental Biology & Medicine
Helen Cserr Memorial Lecturer
President of the American Physiological Society
Bodil M. Schmidt-Nielsen Distinguished Mentor and Scientist Award (American Physiological Society)
Distinguished Scientist of the Society of Experimental Biology & Medicine
Roy G. Daggs Award (American Physiological Society)
College of Biological Sciences Principles of Community Award (lifetime achievement)
Chancellor's Achievement Award for Diversity & Community
AAAS Mentor Award for Lifetime Achievement
Fellow American Physiological Society (inaugural class)

Department and Center Affiliations

Neurobiology, Physiology & Behavior (College of Biological Sciences)
Physology & Membrane Biology (School of Medicine)

ProfessionalSocieties

American Physiological Society (Past President)
Society for Experimental Biology & Medicine (Past President)
Federation of American Societies for Experimental Biology (Previously on Board of Directors)

CBS Grad Group Affiliations

Molecular, Cellular, and Integrative Physiology

Specialties / Focus

Molecular, Cellular, and Integrative Physiology
  • Cellular Physiology

Labs

280 Briggs Hall
  • Jock Hamilton, Sat Chu

Teaching Interests

Cellular physiology; metabolic physiology.
GI physiology

Courses

NPB 114 GI Physiology (Fall)
BIS 298 IMSD Seminar Course (Fall, Winter, Spring)

Publications

7/6/2015 12:48:51 PM
  • The publications listed below are selected from a total of 190.

  • Sekizawa, S-I, B Horwitz, J Horowitz, C-Y Chen.  2013. Protection of signal processing at low temperature in baroreceptive neurons in the nucelus tractus solitarius of Syrian hamsters, a hibernating species.  Am J Physiol Regul, Integr & Comp Physiol, 305 (10) R1153-62.

  • Horwitz, BA, SM Chau, JS Hamilton, C Song, J Gorgone, M Saenz, JM Horowitz, C-Y Chen. 2013, Temporal relationships of blood pressure, heart rate, baroreflex function and body temperature change over a hibernation bout in Syrian hamsters.  Am J Physiol Regul, Integ & Comp Physiol 305 (7): R759-768.

  • Sekizawa, S-I, JM Horowitz, BA Horwitz, C-Y Chen.  2012.  Realignmentof signal processing within a sensory brainstem nucleus, the NTS, as brain temperature declines in the Syrian hamster, a hibernating species.  J Comp Physiol A (Neuroethol Sens Neural Behav Physiol) 198:367-282.

  • Arant, RJ, MS Goo, PD Gill, YH Nguyen, KD Watson, JS Hamilton, JM Horowitz, BA Horwitz 2011.  Decreasing temprature switches hippocampal function from memory formation to modulation of hibernation bout duration in Syrian hamsters. Am J Physiol Regul, Integr & Comp Physiol 301 (2) R438-47.

  • McDonald, RB, KM Walker, DB Warman, SM Griffey, CH Warden, JJ Ramsey, BA Horwitz. 2008.  Characterization of survival and phenotype throughout the life span in UCP2/UCP3 genetically altered mice.  Exp Gerontol 43: 1061-68.

  • Asami, DK, RB McDonald, K Hagopian, BA Horwitz, D Warman, A Hsio, C Warden, JJ Ramsey. 2008. Effect of aging, caoric restriction, and uncoupling protein 3 (UCP3) on mitochondria proton leak in mice.  Exp Gerontol 43:1069-76. 

  • Bronson, NW, JP Piro, JS Hamilton, JM Horowitz, & BA Horwitz.  2006.  Temperature modifies potentiation but not depotentiation in bidirectional hippocampal plasticity of Syrian hamsters (Mesocricetus auratus).  Brain Res 1098: 61-70.

  • Coppola, JD, BA Horwitz, J Hamilton, JE Blevins, RB McDonald.  2005.  Reduced feeding response to muscimol and neuropeptide Y in senescent F344 rats.  Am J Physiol Regul, Integr, & Comp 288:R1492-98.

  • Bronson, NW, JS Hamilton, M. Han, P-A Li, I Hornstra, JM Horowitz, BA Horwitz.  2005.  LOXL null mice demonstrate selective dentate structural changes but maintain dentate granule cell and CA1 pyramidel cell potentiation in the hippocampus.  Neurosci Let 390: 118-122.

  • Coppola, JD, BA Horwitz, J Hamilton, RB McDonald.  2004.  Expression of Neuropeptide Y1 and Y5 receptors in the hypothelamic paraventricular nucleus of aged Fischer 344 rats.  Am J Physiol Regul, Integr, & Comp 287: R69-75. 

  • Ohliger-Frerking P, JM Horowitz, & BA Horwitz. 2003. Serotonergic dorsal raphe neurons from obese zucker rats are hyperexcitable. Neuroscience 120:627-634.
  • Gabaldon AM, DA Gavel, JS Hamilton, RB McDonald, BA Horwitz. 2003. Norepinephrine release in brown adipose tissue remains robust in cold-exposed senescent Fischer 344 rats. Am J Physiol, Regul, Integ & Comp Physiol 285: R91-R98.

  • Horvath, TK, S Diano, S Miyamoto, S Barry, S Gatti, D. Alberati, F. Livak, A Lombardi, M Moreno, F Goglia, G Mor, J Hamilton, D Kachinskas, B. Horwitz, & CH Warden. 2002. Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice. Int J Obesity 27: 433-442.

  • Ohliger-Frerking P, JM Horowitz, & BA Horwitz. 2002. Enhanced adrenergic excitation of serotonergic dorsal Raphe neurons in genetically obese rats. Neurosci Lett. 31: 332:107-112.
  • Horwitz, BA, CA Blanton and RB McDonald. 2002. Physiologic determinants of the anorexia of aging: Insights from animal studies. Ann Rev Nutr 22:417-438

  • Blanton, CA, BA Horwitz, JE Blevins, JS Hamilton, EJ Hernandez and RB McDonald. 2001. Reduced feeding responses to neuropeptide Y in senescent Fischer 344 rats. Am J Physioll Regul, Integr, & Comp 280(4):R1052-60

  • De Fanti BA, DA Gavel, JS Hamilton, and BA Horwitz. 2000. Extracellular hypothalamic serotonin levels after dorsal raphe nuclei stimulation of lean (Fa/Fa) and obese (fa/fa) Zucker rats.  Brain Research. 869:6-14