Georgia Drakakaki

image of Georgia Drakakaki

Assoc. Professor

Departments

Plant Sciences

Offices and Labs

Asmundson 210
(530) 752-1664

Research Interests

Our research is focused on endomembrane trafficking in plant cells. A key area is how trafficking pathways control polysaccharide deposition and plant stress response. Our group employs multidisciplinary research approaches, including the use of small molecules (chemical genomics), organelle proteomics and genetics.

Awards

2014 Excellence in Education Finalist, College of Agricultural and Environmental Sciences

Department and Center Affiliations

Plant Sciences, UCD Energy Institute

CBS Grad Group Affiliations

Biochemistry, Molecular, Cellular and Developmental Biology
Plant Biology

Specialties / Focus

Plant Biology
  • Cell and Developmental Biology
  • Molecular Biology, Biochemistry, and Genomics

Courses

PBI 214 Plant Cell Wall (Fall)
PLS 100AL Plant Metabolic Processes Laboratory-Confocal Microscopy (Fall)
PBI 200B Cell/Developmental Biology- Cell Biology (Winter)
PLS 012 Plants and Society (Winter)

Publications

2/8/2017 10:10:12 PM
  • Davis D, Kang BH, Heringer AS, T.E. W, Drakakaki G (2016). Unconventional Protein Secretion in Plants. Methods Mol Biol. 2016;1459:47-63.

  • Drakakaki G (2015). Polysaccharide deposition during cytokinesis: Challenges and future perspectives Plant Science. 236 177–184

  • Bjornson M, Song X, Dandekar A, Franz A, Drakakaki G, Dehesh K. (2015). A Chemical Genetic Screening Procedure for Arabidopsis thaliana Seedlings. Bio Protoc. Jul 5;5(13). pii: e1519.

  • Henry E, Fung N, Liu J, Drakakaki G, Coaker G (2015). Beyond glycolysis: GAPDHs are multi-functional enzymes involved in regulation of ROS, autophagy, and plant immune responses. PLoS Genet. Apr 28;11(4):e1005199.

  • Hinman SS, Ruiz CJ, Drakakaki G, Wilkop TE, Cheng Q. (2015) On-Demand Formation of Supported Lipid Membrane Arrays by Trehalose-Assisted Vesicle Delivery for SPR Imaging. ACS Appl Mater Interfaces. Aug 12;7(31):17122-30.

  • Davis DJ, McDowell SC, Park E, Hicks G, Wilkop TE, Drakakaki G (2016). The RAB GTPase RABA1e localizes to the cell plate and shows distinct subcellular behavior from RABA2a under Endosidin 7 treatment. Plant Signal Behav. 11(3):e984520.

  • Davis D, Wilkop T.E. and Drakakaki G. The plant Golgi apparatus.in Plant Cells and Their Organelles (William V. Dashek and Gurbachan S. Miglani, eds) W Dashek (Ed.). In press.

  • Worden N, Wilkop TE, Esteve VE, Jeannotte R, Lathe R, Vernhettes S, Weimer B, Hicks G, Alonso J, Labavitch J, Persson S, Ehrhardt D, Drakakaki G (2015). CESA TRAFFICKING INHIBITOR inhibits cellulose deposition and interferes with the trafficking of cellulose synthase complexes and their associated proteins KORRIGAN1 and POM2/CELLULOSE SYNTHASE INTERACTIVE PROTEIN1. Plant Physiol.  Feb;167(2):381-93.

  • Worden N, Esteve VE, Domozych DS, Drakakaki G (2015). Using chemical genomics to study cell wall formation and cell growth in Arabidopsis thaliana and Penium margaritaceum. Methods Mol Biol. 2015;1242:23-39.

  • Park E, Diaz-Moreno S, Davis D, Wilkop TE, Bulone V, and Drakakaki G (2014). Endosidin 7 specifically arrests late cytokinesis and inhibits callose biosynthesis revealing distinct trafficking events during cell plate maturation. Plant Physiology. 165(3):1019-1034.

  • Park E and Drakakaki G (2014). Proteomics of endosomal compartments from plants. Case study: Isolation of trans-Golgi network vesicles. Methods Mol Biol. 1209:179-87

  • Bjornson M, Benn G, Song X, Comai L, Franz AK, Dandekar AM, Drakakaki G, Dehesh K. (2014) Distinct roles for mitogen-activated protein kinase signaling and CALMODULIN-BINDING TRANSCRIPTIONAL ACTIVATOR3 in regulating the peak time and amplitude of the plant general stress response. Plant Physiol. 2014 Oct;166(2):988-96.

  • Drakakaki G and Dandekar A. (2013). Protein secretion: How many secretory routes does a plant cell have? Plant Science (203-204)74–78.

  • Parsons HT, Drakakaki G, Heazlewood JL (2013). Proteomic dissection of the Arabidopsis Golgi and trans-Golgi network. Front Plant Sci. Jan; 3:298.

  • Worden N, Park E, Drakakaki G.(2012) Trans-Golgi Network- An Intersection of Trafficking Cell Wall Components. J Integr, Plant Biol. 54(11):875-86. (cover page article).

  • Worden N, Girke T, Drakakaki G (2014). Plant chemical biology: endomembrane dissection using chemically-induced bioactive clusters. Methods Mol. Biol., 1056:159-68.

  • Parsons H, Ito J, Park E, Carroll A-W, Joshi H-J, Petzold C-J, Drakakaki G and. Heazlewood JL(2012). The Current State of the Golgi Proteomes, Proteomic Applications in Biology, Joshua L. Heazlewood and Christopher J. Petzold (Ed.), ISBN: 978-953-307-613-3, InTech.
  • Drakakaki G, Robert S, Szatmari AM, Brown MQ, Nagawa S, Van Damme D, Leonard M, Yang Z, Girke T, Schmid SL, Russinova E, Friml J, Raikhel NV, Hicks GR. (2011) Clusters of bioactive compounds target dynamic endomembrane networks in vivo. Proc Natl Acad Sci U S A. 108 (43):17850-5.
  • Drakakaki G, van de Ven W, Pan S, Miao Y, Wang J, Keinath N, Weatherly B, Jiang L, Schumacher K, Hicks G, Raikhel N. (2012). Isolation and proteomic analysis of the SYP61 compartment reveal its role in exocytic trafficking in Arabidopsis. Cell Research. 22: 413-424.
  • Drakakaki G, Robert S and Hicks G. (2009) Chemical dissection of endomembrane pathways. Plant Signaling & Behavior.4(1):57-62.
  • Zabotina O, van de Ven W, Freshour G, Drakakaki G, Cavalier D, Mouille G, Hahn M, Keegstra K, and Raikhel, N (2008). The Arabidopsis XT5 protein encodes a putative α-1,6-xylosyltransferase that is involved in xyloglucan biosynthesis. Plant Journal. 56(1):101-15.
  • Robert S, Chary N, Drakakaki G, Li S, Yang Z, Raikhel N, and Hicks G (2008). Endosidin1 defines a compartment involved in endocytosis of the brassinosteroid receptor BRI1 and the auxin transporters PIN2 and AUX1. Proc Natl Acad Sci U S A. 105(24):8464-9.
  • Cocuron J-C, Lerouxel O, Drakakaki G, Alonso A P, Liepman AH, Keegstra K, Raikhel N, and Wilkerson CG (2007). A gene from the cellulose synthase-like C family encodes a beta-1,4 glucan synthase. Proc Natl Acad Sci U S A. 15;104(20):8550-5.
  • Drakakaki G, Zabotina O, Delgado I, Robert S, Keegstra K and Raikhel N (2006). Arabidopsis reversibly glycosylated polypeptides 1 and 2 are essential for pollen development. Plant Physiology 142: 1480-1492.
  • Drakakaki G, Marcel M, Arcalis E, Altman F, Gonzalez-Melendi P, Fischer R, Christou P, and Stoger E (2006) b. The intracellular fate of recombinant phytase is tissue-dependent. Plant Physiology 141: 578-586.
  • Drakakaki G, Marcel M, Glahn R, Lund L, Periagh S, Christou P, and Stoger E (2005). Endosperm specific co-expression of recombinant soybean ferritin and Aspergillus phytase in maize results in significant increases in the levels of bioavailable iron. Plant Molecular Biology 59: 869-880.