NLRs and PRRs function in innate immune signaling
Programmed cell death (PCD)
Pathogen effector biology
Genomics and Proteomics
Department and Center Affiliations
CBS Grad Group Affiliations
Specialties / Focus
- Molecular Biology, Biochemistry, and Genomics
- Genomics, Proteomics and Metabolomics
- Signal Transduction and Gene Regulation
- Structural and Mechanistic Biochemistry
- Plant Biochemistry and Molecular Biology
- Organelle and Cytoskeleton Dynamics
- Cell Biology
- Cellular Responses to Toxins and Stress
Padmanabhan, M., and S.P. Dinesh-Kumar (2014). The conformational and subcellular compartmental dance of plant NLRs during viral recognition and defense signaling. Cutt Op Microbiol. 20:55-61.
Woo J, Park E, and Dinesh-Kumar SP. (2014) Differential processing of Arabidopsis ubiquitin-like Atg8 autophagy proteins by Atg4 cysteine proteases. Proc. Natl. Acad. Sci. 111:863-868.
Ma S, Shah S, Bohnert HJ, Snyder M, Dinesh-Kumar SP. (2013) Incorporating motif analysis into gene co-expression networks reveals novel modular expression pattern and new signaling pathways. PLoS Genetics 9(10): e1003840.
Padmanabhan M, Ma S, Burch-Smith T, Czymmek K, Huijser P, and Dinesh-Kumar SP (2013) Novel Positive Regulatory Role for the SPL6 Transcription Factor in the N TIR-NB-LRR Receptor-Mediated Plant Innate Immunity. PLoS Pathogens 9(3):e1003235.
Ma S, Bachan S, Porto M, Bohnert HJ, Snyder M, Dinesh-Kumar SP. (2012) Discovery of stress responsive DNA regulatory motifs in Arabidopsis. PLoS ONE 7:e43198.
Hayward, AP and Dinesh-Kumar, SP (2011) What can Plant Autophagy do for an Innate Immune Response? Annu Rev Phytopathol. 49:557-576
Lee, H.Y., Bowen, C.H., Popescu, G.V., Kang, H., Kato, N., Ma, S., Dinesh-Kumar, S.P., Snyder, M., and Popescu, S.C. (2011) Arabidopsis RTNLB1 and RTNLB2 reticulon-like proteins regulate intracellular trafficking and activity of the FLS2 immune receptor. Plant Cell 23:3374-3391.
Zhu X, Caplan JC, Mamillapalli P, Czymmek K, and Dinesh-Kumar SP (2010) Function of endoplasmic reticulum calcium ATPase in innate immunity mediated programmed cell death. EMBO J 29, 1007-1018.
Padmanabhan M, and Dinesh-Kumar SP (2010) All Hands on Deck - the Role of Chloroplasts, ER and Nucleus in Driving Plant Innate Immunity. Mol Plant Microbe Interact 23, 1368-1380.
Zhu X, Pattathil S, Mazumder K, Brehm A, Hahn M, Dinesh-Kumar SP, and Joshi C. (2010) Virus-induced gene silencing offers a functional genomics platform for studying plant cell wall formation. Mol Plant 3, 818-833. (Cover Article).
*Caplan JC, *Zhu X, (contributed equally), Mamillapalli P, Marathe R, Anandalakshmi R, and Dinesh-Kumar SP. (2009) Induced ER-chaperones regulate a receptor-like kinase to mediate anti-viral innate immune response in plants. Cell Host Microbe 6, 457-469.
Popescu SC, Popescu GV, Bachan S, Zhang Z, Gerstein M, Snyder M, and Dinesh-Kumar SP. (2009) MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Genes Develop 23:80-92.
Caplan JC, Mamillapalli P, Burch-Smith TM, Czymmek K, and Dinesh-Kumar SP. (2008) Chloroplastic protein NRIP1 mediates innate immune receptor recognition of a viral effector. CELL 132:449-462.
Caplan JC, Padmanabhan M, and Dinesh-Kumar SP. (2008) Plant NB-LRR immune receptors: From recognition to transcriptional reprogramming. Cell Host Microbe 3:126-135.
Patel S, and Dinesh-Kumar SP. (2008) Arabidopsis ATG6 is required to limit the pathogen-associated cell death response. Autophagy 4:20-27.
Burch-Smith TM, Schiff M, Caplan J, Tsao J, Czymmek K, and Dinesh-Kumar SP. (2007) A novel role for the TIR domain in association with pathogen-derived elicitors. PLoS Biol 5:e68:501-514.
Liu Y, Schiff M, Czymmek K, Talloczy Z, Levine B, Dinesh-Kumar SP. (2005) Autophagy regulates programmed cell death during the plant innate immune response. Cell 121:567-577.
Meenu Padmanabhan-Research Specialist; Shisong Ma-Research Specialist; Jongchan Woo-Post-doc; Ugrappa Nagalakshmi-Research Scientist; Neeraj Lal-BMCDB Graduate Student; Parameswari Jayakumar-Visiting Scientist, Sugarcane Research Institute, India; Adriana Bernal-Visiting Professor,Universidad de los Andes, Bogotá, Colombia; Burinrutt Thanasuwat-Undergraduate Student; Barry Chan-Undergraduate Student; Cody Burr-Undergraduate Student; Janet Tan-Undergraduate Student; Lynh Nguyen-Undergraduate Student; Kingsley Lim-Undergraduate Student