NLRs and PRRs function in innate immune signaling
Programmed cell death (PCD)
Pathogen effector biology
Genomics and Proteomics
Department and Center Affiliations
CBS Grad Group Affiliations
Specialties / Focus
- Molecular Biology, Biochemistry, and Genomics
- Genomics, Proteomics and Metabolomics
- Cell Biology
- Cellular Responses to Toxins and Stress
Ugrappa Nagalakshmi-Research Scientist; Shisong Ma-Research Specialist; Meenu Padmanabhan-Research Specialist; Jongchan Woo-Research Specialist; Eunsook Park-Postdoc; Neeraj Lal-BMCDB Graduate Student; Hye-Young Lee-Visting Graduate Student, Seoul National University; Adriana Bernal-Sabbatical Scientist, Universidad de los Andes, Colombia; Burinrutt Thanasuwat-Specialist; Barry Chan-Specialist; Jonghoon Chang-Undergraduate Student; Janet Tan-Undergraduate Student; Lynh Nguyen-Undergraduate Student; Andrey Jenkins-Undergraduate student
Caplan, J., Kumar, AS., Park, E., Padmanabhan, M., Hoban, K., Modla, S., Czymmek, K., and Dinesh-Kumar, SP. (2015). Chloroplast stromules function during innate immunity. Dev Cell 34:45-57. (Cover Article).
See Preview: Gu, Y and Dong, X (2015)Stromules: Signal Conduits for Plant Immunity. Dev Cell 34: 3-4.
Editor's choice: VanHook A (2015) Immunity pipelines. Sci. Signal 8:ec191.
Ali, Z., Abul-Faraj, A., Li, L., Ghosh, N., Piatek, M., Mahjoub, A., Aouida, M., Piatek, A., Baltes, N., Voytas, D., Dinesh-Kumar, S.P., Mahfouz, M. (2015) Efficient virus-mediated genome editing in plants using the CRISPR/Cas9 system. Mol Plant S1674-2052(15)00162-8.
Manohar, M., Tian, M., Moreau, M., Park, S., Choi, H., Fei, Z., Friso, G., Asif, M., Manosalva, P., von Dahl C., Shi, K., Ma, S., Dinesh-Kumar, S.P., O’Doherty, I., Schroeder, F., van Wijk, K., and Klessig, D. (2015) Identification of multiple salicylic acid-binding proteins using two high throughput screens. Front Plant Sci 5:777.
Woo J, Park E, and Dinesh-Kumar SP. (2014) Differential processing of Arabidopsis ubiquitin-like Atg8 autophagy proteins by Atg4 cysteine proteases. Proc. Natl. Acad. Sci. 111:863-868.
Padmanabhan, M., and S.P. Dinesh-Kumar (2014). The conformational and subcellular compartmental dance of plant NLRs during viral recognition and defense signaling. Cutt Op Microbiol. 20:55-61.
Padmanabhan M, Ma S, Burch-Smith T, Czymmek K, Huijser P, and Dinesh-Kumar SP (2013) Novel Positive Regulatory Role for the SPL6 Transcription Factor in the N TIR-NB-LRR Receptor-Mediated Plant Innate Immunity. PLoS Pathogens 9(3):e1003235.
Ma S, Shah S, Bohnert HJ, Snyder M, Dinesh-Kumar SP. (2013) Incorporating motif analysis into gene co-expression networks reveals novel modular expression pattern and new signaling pathways. PLoS Genetics 9(10): e1003840.
Ma S, Bachan S, Porto M, Bohnert HJ, Snyder M, Dinesh-Kumar SP. (2012) Discovery of stress responsive DNA regulatory motifs in Arabidopsis. PLoS ONE 7:e43198.
Hayward, AP and Dinesh-Kumar, SP (2011) What can Plant Autophagy do for an Innate Immune Response? Annu Rev Phytopathol. 49:557-576
Zhu X, Caplan JC, Mamillapalli P, Czymmek K, and Dinesh-Kumar SP (2010) Function of endoplasmic reticulum calcium ATPase in innate immunity mediated programmed cell death. EMBO J 29, 1007-1018.
*Caplan JC, *Zhu X, (contributed equally), Mamillapalli P, Marathe R, Anandalakshmi R, and Dinesh-Kumar SP. (2009) Induced ER-chaperones regulate a receptor-like kinase to mediate anti-viral innate immune response in plants. Cell Host Microbe 6, 457-469.
Popescu SC, Popescu GV, Bachan S, Zhang Z, Gerstein M, Snyder M, and Dinesh-Kumar SP. (2009) MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Genes Dev 23:80-92.
Caplan JC, Mamillapalli P, Burch-Smith TM, Czymmek K, and Dinesh-Kumar SP. (2008) Chloroplastic protein NRIP1 mediates innate immune receptor recognition of a viral effector. CELL 132:449-462.
Caplan JC, Padmanabhan M, and Dinesh-Kumar SP. (2008) Plant NB-LRR immune receptors: From recognition to transcriptional reprogramming. Cell Host Microbe 3:126-135.
Patel S, and Dinesh-Kumar SP. (2008) Arabidopsis ATG6 is required to limit the pathogen-associated cell death response. Autophagy 4:20-27.
Burch-Smith TM, Schiff M, Caplan J, Tsao J, Czymmek K, and Dinesh-Kumar SP. (2007) A novel role for the TIR domain in association with pathogen-derived elicitors. PLoS Biol 5:e68:501-514.
Liu Y, Schiff M, Czymmek K, Talloczy Z, Levine B, Dinesh-Kumar SP. (2005) Autophagy regulates programmed cell death during the plant innate immune response. Cell 121:567-577.