Liping Huang

image of Liping Huang

Adjunct Associate Professor

Departments

Nutrition

Offices and Labs

206 WHNRC
5307545756

Degrees

1995 PhD Molecular Virology University of Iowa
1983 MD Medicine and Public Health Shanghai Medical University

Research Interests

Dr. Huang has primarily focused on mammalian zinc transporter proteins and their roles in maintaining body zinc homeostasis, regulating body adiposity, and modifying insulin expression. She is also interested in the molecular mechanisms by which zinc and lunasin reduce the risk of prostate cancer. Her work involves cell lines and mice to investigate the roles of zinc in reduction of prostate cancer risk and in regulation of body weight, body fat, and insulin resistance.

Department and Center Affiliations

Nutrition
Center of Excellence for Nutritional Genomics

ProfessionalSocieties

Society for Zinc Biology
The American Society for Biochemistry and Molecular Biology

CBS Grad Group Affiliations

Integrated Genetics and Genomics

Specialties / Focus

Integrated Genetics and Genomics
  • Animal Genomics

Graduate Groups not Housed in CBS

Nutrition Graduate Group

Publications

8/17/2011 3:27:01 PM
  • Tepaamorndech S, Huang L, Kirschke CP. 2011. A null-mutation in the Znt7 gene accelerates prostate tumor formation in a transgenic adenocarcinoma mouse prostate model. Cancer Lett. 308:33-42.
  • Galvez AF, Huang L, Magbanua MJ, Dawson K, Rodriguez RL. 2011 Lunasin peptide upregulates thrombospondin 1 (THBS1) gene expression in non-tumorigenic prostate epithelial cells. Nutrition and Cancer, 63:623-36.
  • Huang, L, Yan M, Kirschke CP. 2010. Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic b-cells by promoting insulin gene transcription. Exp. Cell Res. 316:2630-43.
  • Kirschke CP, Huang L. 2008. Expression of ZNT (SLC30) family members in the epithelium of the mouse prostate during sexual maturation. J. Mol. Histol. 39:359-370.
  • Huang L, Yu YY, Kirschke CP, Gertz ER, Lloyd KK. 2007. Znt7 (Slc30a7)-deficient mice display reduced body zinc status and body fat accumulation. J. Biol. Chem. 282:37053-37063.
  • Huang L, Kirschke CP. 2007. A di-leucine sorting signal in ZIP1 (SLC39A1) mediates endocytosis of the protein. FEBS J. 274:3986-3997.
  • Yu YY, Kirschke CP, Huang L. 2007. Immunohistochemical analysis of ZnT1, 4, 5, 6, and 7 in the mouse gastrointestinal tract. J.Histochem. Cytochem. 55:223-234.
  • Huang L, Kirschke CP, Zhang Y. 2006. Decreased intracellular zinc in human tumorigenic prostate epithelial cells: a possible role in prostate cancer progression. Cancer Cell Int. 31;6:10.
  • Huang L, Kirschke CP, Zhang Y, Yu YY. 2005. The ZIP7 gene (Slc39a7) encodes a zinc transporter involved in zinc homeostasis of the Golgi apparatus. J Biol Chem. 280:15456-63.