Amparo Villablanca

image of Amparo Villablanca

Professor, Cardiovascular Medicine

Departments

Cardiovascular Physio(IntMed)

Offices and Labs

TB 172
(530) 752-0717; 752-0718

Profile Introduction

Vascular biology, hormonal regulation of gene expression in tissues and cells, atherosclerosis, mouse biology, women's health.

Degrees

1990 Cardiovascular Medicine - Fellowship University of California,Davis
1986 Internal Medicine - Residency University of California, Davis
1983 MD University of California, Davis
1979 BS Psychobiology University of California, Los Angeles

Research Interests

Vascular biology, hormonal regulation of gene expression in tissues and cells, atherosclerosis, mouse biology, women's health.

Awards

1999 Distinguished Alumna of the Year Award, UC Davis School of Medicine
2000 Woman of Achievement in Medicine Award, Capitol Business and Professional Women Association, Sacramento, CA
2003- Fellow, American Heart Association (FAHA) Council on Atherosclerosis, Thrombosis and Vascular Biology
2007 Recipient, Heart of Gold Award, American Heart Association

Department and Center Affiliations

Department of Internal Medicine, Division of Cardiovascular Medicine
Associate Director, Women's Center for Health
Director, Hormones and Atherosclerosis Laboratory, Mouse Biology Program, Center for Comparative Medicine, UC Davis

ProfessionalSocieties

American Heart Association, Council on Atherosclerosis, Thrombosis and Vascular Biology

CBS Grad Group Affiliations

Molecular, Cellular, and Integrative Physiology

Specialties / Focus

Molecular, Cellular, and Integrative Physiology
  • Cardiorespiratory Physiology
  • Cellular Physiology
  • Molecular Physiology

Field Sites

Surge III

Teaching Interests

Multiple courses for undergraduates,medical students, physicians and allied health professional continuing medical education, and community/lay groups.

Publications

5/21/2010 9:26:34 AM
  • Corbacho, AM, Eiserich, JP, Zuniga, LA, Valacchi, G, Cross, CE, and Villablanca, AC. Compromised Aortic Vasoreactivity in Male Estrogen Receptor-Alpha Deficient Mice During Acute Lipopolyssacharide-Induced Inflammation. (2006, in press, Endocrinology).
  • Benton, J., Powers, A., Eiselein, L., Fitch, R., Wilson, D., Villablanca, A.C., and Rutledge, J. Hyperglycemia and loss of ovarian hormones mediate atheroma formation through endothelial layer disruption and increased permeability (2006, in press, American J. Physiology: Regulatory, Integrative and Comparative Physiology, special issue on gender and cardiovascular disease).
  • Wang-Polagruto, J.,Villablanca, A.C., Polagruto, J, Lee, L.., Holt, RA., Schrader, H., Ensunsa, J., Steinberg, FM., Schmitz, H., and Keen, CL. Chronic Consumption of Flavanol-rich Cocoa Improves Endothelial Function and Decreases Vascular Cell Adhesion Molecule (VCAM-1) in Hypercholesterolemic Postmenopausal Women (J. Cardiovascular Pharmacology, 47[Suppl 2]:S177-S186, 2006.
  • Villablanca, A.C., Lubhan, D, Shelby, L., Lloyd, K, and Barthold, S. Susceptibility to early atherosclerosis in male mice is mediated by estrogen receptor a (ERa). Atherosclerosis, Thrombosis and Vascular Biology, 24:1055-1061, 2004 (with journal editorial). Erratum in: Arterioscler Thromb Vasc Biol. 2004, 24(6):1055-1061.
  • Steinberg, F.M., Guthrie, N.G., Villablanca, A.C., Kumar, K., and Murray, M.J. In healthy post-menopausal women soy isoflavones have favorable effects on endothelial function, which are independent of lipid and antioxidant effects. Amer. J. Clinical Nutrition, 78:123-130, 2003.
  • Villablanca, A.C., K.A. Lewis and J.C. Rutledge. Differential regulation of gene expression by ovariectomy in mouse aorta. Physiological Genomics 12:175-185, 2003.
  • Villablanca AC, Lewis KA and JC Rutledge. 2002. Time- and dose-dependent differential upregulation of three genes by 17 beta-estradiol in endothelial cells. J Appl Physiol. 92(3):1064-1073
  • Villablanca AC. 1998. Nicotine stimulates DNA synthesis and proliferation in vascular endothelial cells in vitro. J Appl Physiol. 84(6):2089-2098
  • Villablanca AC and MR Hanley. 1997. 17 beta-estradiol stimulates substance P receptor gene expression. Mol Cell Endocrinol. 135(2):109-117