Abhaya M. Dandekar
Offices and Labs
|1982||Post Doc||Molecular Biology||National Institutes of Health, USA|
|1979||PhD||Microbiology||M.S. University of Baroda, India|
|1974||MSc||Microbiology||M.S. University of Baroda, India|
Molecular, biochemical and genomic dissection of phenotypic traits in fruit trees
Plant phenotypes describe the physiological and genetic basis of agriculturally significant problems. My laboratory is interested in dissecting phenotypic traits to define the underlying molecular genetics, physiological and biochemical mechanisms that regulate their expression. Our focus is on trees and on phenotypic traits that regulate productivity and quality of fruit and nuts. We categorize genes through the analysis of their encoded functional products, mRNA, small RNA, proteins and/or metabolites that contribute to the genetic basis of phenotypic traits. An outcome of this effort is the discovery of novel genes, the development of trait specific diagnostic tools and therapeutic strategies.
Department and Center Affiliations
CBS Grad Group Affiliations
Specialties / Focus
- Molecular Biology, Biochemistry, and Genomics
- Integrated Genetics and Genomics
- Computational Biology
- Synthetic Biology
Graduate Groups not Housed in CBS
Escobar, M.A., E.L. Civerolo, K.R. Summerfelt and A.M. Dandekar. 2001. RNAi-mediated oncogene silencing confers resistance to crown gall tumorigenesis. Proc. Nat. Acad. Sci. U.S.A. 98: 13437-13442.
Koichiro Ushijima, K., H. Sassa, A.M. Dandekar, T.M. Gradziel, R. Tao, and H. Hirano. 2003. Structural and transcriptional analysis of self-incompatibility (S) locus of almond (Prunus dulcis): identification of a pollen-expressed F-box gene with haplotype-specific polymorphism. Plant Cell 15(3): 771-781.
Dandekar, A.M., G. Teo, B.G. Defilippi, S.L. Uratsu, A.J. Passey, A.A. Kader, J. R. Stow, R.J. Colgan and D.J. James. 2004. Effect of down-regulation of ethylene biosynthesis on fruit flavor complex in apple fruit. Transgenic Res. 13: 373-384.
Aguero, C.B., Uratsu, S.L., Greve, L.C., Powell, A.L.T., Labavitch, J.M., Meredith, C.P. and Dandekar, A.M. 2005. Evaluation of tolerance to Pierce’s Disease and Botrytis in transgenic plants of Vitis vinifera L. Expressing the Pear PGIP gene. Molecular Plant Pathology 6(1) 43-51.
Barckley, K.K., S.L. Uratsu, T.M. Gradziel and A.M. Dandekar. 2006. Multidimensional Analysis of S-alleles from Cross-Incompatible Groups of California Almond Cultivars. J. Am. Soc. Hort. Sci. 131: 632-636.
Sudarshana, M.R., M.A Plesha, S.L. Uratsu, B.W. Falk, A.M. Dandekar, T-K. Huang and K.A. McDonald. 2006. A chemically inducible cucumber mosaic virus amplicon system for expression of heterologous proteins in plant tissues. Plant Biotechnology J. 4: 551-559.
Martinelli, F., S.L. Uratsu, R.L. Reagan, Y. Chen, D. Tricoli, O. Fiehn, D.M. Rocke, C.S. Gasser and A.M. Dandekar. 2009. Gene regulation in parthenocarpic tomato fruit. J. Exptl. Bot. 60(13): 3873-3890.
Kumar, P., S. Uratsu, A. Dandekar and B. Falk. 2009. Tomato bushy stunt virus recombination guided by introduced miRNA target sequences. J. Virol. 83 (20): 10472-10479.
Muir, R.M., A.M. Ibanez, S.L. Uratsu, E.S. Ingham, C.A. Leslie, G.H. McGranahan, N. Batra, S. Goyal., J. Joseph., E.D. Jemmis and A.M. Dandekar 2011. Mechanism of gallic acid biosynthesis in bacteria (E.coli) and walnut (J.regia). Plant Mol. Biol. 75: 555-565.
Akagi, A., A. Dandekar and H. Stotz. 2011. Resistance of Malus domestica fruits to Botrytis cinerea depends on endogenous ethylene biosynthesis. Phytopathol. 101 (11): 1311-1321.
Wu, J., Y.Q. Gu. Y. Hu, F.M. You, A.M. Dandekar, C.A. Leslie, M. Aradhaya, J. Dvorak and M-C. Luo. 2012. Characterizing the walnut genome through analysis of BAC end sequences. Plant Mol. Biol. 78: 95-107.
Dandekar, A.M., H. Gouran, A.M. Ibanez, S.L. Uratsu, C.B. Aguero, S.McFarland, Y. Borhani, P.A. Fieldstein, G.E. Bruening, R. Nascimento, L. Goulart, P.E. Pardington, A. Choudhary, M. Norvell, R. Civerolo and Goutam Gupta. 2012. An engineered innate immune defense protects grapevines from Pierce’s Disease. Proc. Nat. Acad. Sci. USA 109(10): 3721-3725.
Martinelli, F., S.L. Uratsu, U. Albrecht, R.L. Reagan, M.L. Phu, M. Britton, V. Buffalo, J. Fass, E. Leicht, W. Zhao, D. Lin, R.D. D’Souza, C.E. Davis, K.D. Bowman and A.M. Dandekar. 2011. Transcriptome profiling of citrus fruit response to huanglongbing disease. PLoS ONE 7(5): e38039. doi:10.1371/journal.pone.0038039.
You, F.M., K.R. Deal, J. Wang, M.T. Britton, J.N. Fass, D. Lin, A. Dandekar, C.A. Leslie, M. Aradhya, M-C. Luo and J. Dvorak. 2012. Genome-wide SNP discovery in walnut with an AGSNP pipeline updated for SNP discovery in allogamous organisms. BMC Genomics 13: 354 doi:10.1186/1471-2164-13-354.
Martinelli, F., R.L. Reagan, S.L. Uratsu, M.L. Phu, U. Albrecht, W. Zhao, C.E. Davis, K.D. Bowman and A.M. Dandekar. 2013. Gene regulatory networks elucidating Huanglongbing disease mechanisms. PLoS ONE Sep 25;8(9):e74256. doi: 10.1371/journal.pone.0074256.
Walawage, S.L., M.T. Britton, C.A. Leslie, S.L. Uratsu, Y-Y. Li and A.M. Dandekar. 2013. Stacking Resistance to Crown Gall and Nematodes in Walnut Rootstocks. BMC Genomics 14(1): 668-681.
Chakraborty S., R. Minda, L. Salaye, A.M. Dandekar, S.K. Bhattacharjee and B.J. Rao. 2013. Promiscuity-based enzyme selection for rational directed evolution experiments. In, J. Samuelson (ed.), “Enzyme Engineering: Methods and Protocols”. Pub: Springer New York. Methods in Molecular Biology. 978: 205-216.
Ibanez, A.M. F. Martinelli, R.L. Reagan, S.L. Uratsu, A.Vo, M.A. Tinoco, M.L. Phu, Y. Chen, D.M. Rocke and A.M. Dandekar. 2014. Transcriptome and metabolome analysis to elucidate puffing disorder in citrus. Plant Sci. 217-218: 87-98.
Luo, M-C., F.M. You, P. Li, J-R. Wang, T.Wu, A.M. Dandekar, C.A. Leslie, M. Aradhaya, P.E. McGuire and J. Dvorak. 2015. Synteny analysis in Rosids with the walnut physical map reveals a suite of genomic characteristics common to long-lived woody perennials. BMC Genomics 16:707 (DOI 10.1186/s12864-015-1906-5).
Wu, T., Y. Wang, Y. Zheng, Z. Fei, A. Dandekar, K. Xu, Z. Han and L. Cheng. 2015. Suppressing sorbitol synthesis substantially alters the global expression profile of stress response genes in apple (Malus Domestica) leaves. Plant & Cell. Physiol. 56(9): 1748-1761.