Robert H Weiss

image of Robert H Weiss

Professor

Departments

Chief of Nephrology, Sacramento VA Medical Center
Nephrology (Internal Med)

Offices and Labs

GBSF rm 6312
(530) 752-4010

Profile Introduction

cyclins and cyclin inhibitors, cancer growth control, metabolomics and proteomics, polycystic kidney disease

Degrees

1991 Fellowship, Nephrology University of California, San Francisco
1984 MD Medicine University of California, Irvine
1980 MS Medical Physics University of California, Los Angeles
1978 MS Physical Chemistry University of California, Los Angeles
1976 BA Chemistry University of California, Santa Cruz

Research Interests

cyclins and cyclin inhibitors, cancer growth control, metabolomics and proteomics, polycystic kidney disease

Department and Center Affiliations

UC Davis Cancer Center

CBS Grad Group Affiliations

Molecular, Cellular, and Integrative Physiology
Integrated Genetics and Genomics

Specialties / Focus

Biochemistry, Molecular, Cellular and Developmental Biology
  • Cell Biology
  • Cell Division and the Cytoskeleton
  • Molecular Medicine
  • Metabolism and Molecular Physiology
Molecular, Cellular, and Integrative Physiology
  • Molecular Physiology

Graduate Groups not Housed in CBS

Immunology Comparative Pathology
Comparative Pathology

Publications

5/21/2010 9:26:34 AM
  • Weiss RH, Joo A and CJ Randour. 2000. p21Waf1/Cip1 is an assembly factor required for PDGF-induced vascular smooth muscle cell proliferation. Journal of Biological Chemistry. 275:10285-10290
  • Davis BB, Thompson DA, Howard LL, Morisseau C, Hammock BD and RH Weiss. 2002. Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. Proceedings of the National Academy of Sciences (USA). 99(4):2222-2227
  • Lin, P.Y., Fosmire, S.P., Baksh, S., Modiano, J.F., Weiss, R.H. Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance, Molecular Cancer, 6:16, 2007
  • Park, S.H., Park, J.Y., Weiss, R.H. Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA-damaging chemotherapy associated with enhancement of phospho-p53, Journal of Urology 180(1):352-60, 2008
  • Park, S.H., Wang, X., Liu, R., Lam, K.S., Weiss, R.H. High throughput screening of a small molecule one-bead-one-compound combinatorial library to identify attenuators of p21 as chemotherapy sensitizers, Cancer Biology & Therapy, 7(12), 2015-22, 2008
  • Kim, K.M., Aronov, P.A., Zakharkin, S.O., Anderson, D., Perroud, B., Weiss, R.H., Urine metabolomic analysis for kidney cancer detection and biomarker discovery, Molecular and Cellular Proteomics, 8(3):558-70, 2009
  • Perroud, B., Ishimaru, T., Borowsky, A.D., Weiss, R.H. Grade-dependent proteomic characterization of kidney cancer, Molecular and Cellular Proteomics, May;8(5):971-85, 2009
  • Liu , J.-Y. Park, S.-H., Morisseau , C., Hwang , S. H., Hammock, B., Weiss, R.H., Sorafenib Has sEH Inhibitory Activity Which Contributes to Its Effect Profile in vivo, Molecular Cancer Therapeutics, 2009 Aug;8(8):2193-203, 2009
  • Taylor, S.L., Ganti, S., Bukanov N.O., Chapman, A., Fiehn, O., Osier, M., Kim, K., Weiss, R.H. A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease, American Journal of Physiology: Renal Physiology, in press, 2010
  • Weiss, R.H. p21Waf1/Cip1 as a therapeutic target in breast and other cancers, Cancer Cell, 4: 426-429, 2003