John Rutledge

image of John Rutledge

Professor

Departments

Cardiovascular Physio(IntMed)

Offices and Labs

Genome and Biomedical Sciences Facility
530-752-4713

Profile Introduction

Vascular biology, vascular inflammation, diabetic vasculopathy, lipoproteins, gender effects on the vascular wall pathology, maternal-fetal imprinting

Degrees

1976 MD - Baylor College of Medicine
1972 BA Biology University of Texas

Research Contribution

Hypertension and Microcirculation NIH Study Section

Research Interests

Vascular biology, vascular inflammation, diabetic vasculopathy, lipoproteins, gender effects on the vascular wall pathology, maternal-fetal imprinting

Awards

Richard A. and Nora Eccles Harrison Endowed Chair in Diabetes Research
Dean's Award for Excellence in Mentoring

Department and Center Affiliations

Center for Biophotonics Science and Technology
Clinical and Translational Science Center
Foods for Health Institute

ProfessionalSocieties

American Heart Association
American Physiology Society
American Association for the Advancement of Science

CBS Grad Group Affiliations

Molecular, Cellular, and Integrative Physiology

Specialties / Focus

Molecular, Cellular, and Integrative Physiology
  • Cardiorespiratory Physiology
  • Metabolic Physiology

Graduate Groups not Housed in CBS

Nutritional Sciences

Labs

Rutledge Laboratory
  • Robin Altman-MCIP graduate student, Kit Ng-MCIP graduate student, Hnin Hnin Aung-project scientist, Collin Ellis-Nutrition Sciences Graduate student, Al Sarieh-lab technician, Romobia Hutchinson-lab technician

Teaching Interests

<ul><li>Scientific proposal writing workshop<li>Cardiovascular physiology and pathophysiology
website

Publications

5/21/2010 9:26:34 AM
  • Mullick AE, Powers AF, Kota RS, Tetali SD, Eiserich JP, Rutledge JC. Apolipoprotein E3- and nitric oxide- dependent modulation of endothelial cell inflammatory responses. Arterioscler Thromb Vasc Biol 2007;27(2):339-345.
  • Motton DD, Keim NL, Tenorio FA, Horn WF, Rutledge JC. Postprandial monocyte activation in response to meals with high and low glycemic loads in overweight women. Am J Clin Nutr 2007;85:60-65.
  • Eiselein L, Wilson D, Lame M. Rutledge JC. Lipolysis products from triglyceride-rich lipoproteins increase endothelial permeability, perturb zonula occludens-1, F-actin, and induce apoptosis. Am J Physiol Heart Circ Physiol 2007 Jan 26;[Epub ahead of print]
  • Wang L, Sapuri-Butti AR, Aung HH, Parikh AN, Rutledge JC. Triglyceride-rich lipoprotein lipolysis increases aggregation of endothelial cell membrane microdomains and produces reactive oxygen species. Am J Physiol Heart Circ Physiol. 2008. 295(1):H237-44.
  • Wang L, Gill R, Pedersen TL, Higgins LJ, Newman JW, Rutledge JC. Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized free fatty acids that Induce endothelial cell inflammation. J Lipid Res. 2009; 50, 204-213
  • Villablanca AC, Tenwolde A, Lee M, Huck M, Mumenthaler S, Rutledge JC. 17beta-Estradiol Prevents Early-Stage Atherosclerosis in Estrogen Receptor-Alpha Deficient Female Mice. J Cardiovasc Transl Res. 2009;2:289-299
  • Barnholt K, Kota R, Aung HH, Rutledge JC. Adenosine blocks interferon-γ-induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation. Journal of Immunology. 2009;183,6767-6777.