Bruce D. Hammock
Professor of Entomology
Offices and Labs
Profile IntroductionThe laboratory has several major areas. We are interested in control of development by lipid chemical mediators. In mammals we work on enzyme regulation of epoxyeicosanoids that control pain, hypertension and inflammation. In particular we are working to move a small molecule drug to the clinic regulating these lipid mediators and treating diabetes and pain. We also are looking at the effect of diet on these systems. We also work on the development of high throughput systems for metabolite profiling by mass spectrometry (metabolomics) and on immunoassays (biosensors) to monitor human exposure to environmental contaminants. We currently are using recombinant alpaca nanobodies in biosensor formats.
|1973||PhD||Entomology (Toxicology)||University of California, Berkeley|
|1969||BS||Entomology (Chemistry)||Louisiana State University|
See laboratory publications on web site for current areas.
Technically we are a diverse laboratory applying a variety of tools in biological chemistry to questions in regulatory biology. We attempt to relate our fundamental work to human and environmental health. The technologies include enzymology, physiology, medicinal chemistry, analytical chemistry and others.
Department and Center Affiliations
CBS Grad Group Affiliations
Graduate Groups not Housed in CBS
646. Ai, D., Y. Fu, D. Guo, H. Tanaka, N. Wang, C. Tang, B.D. Hammock, J.Y-J. Shyy and Y. Zhu. 2007. Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. P. Natl. Acad. Sci. USA. 104:9018-9023.
For current publication see laboratory web site. http://www.biopestlab.ucdavis.edu/