Bruce D. Hammock

image of Bruce D. Hammock

Professor of Entomology


UCD Cancer Research Center

Offices and Labs

90 Briggs Hall

Profile Introduction

The laboratory has several major areas. We are interested in control of development by lipid chemical mediators. In mammals we work on enzyme regulation of epoxyeicosanoids that control pain, hypertension and inflammation. In particular we are working to move a small molecule drug to the clinic regulating these lipid mediators and treating diabetes and pain. We also are looking at the effect of diet on these systems. We also work on the development of high throughput systems for metabolite profiling by mass spectrometry (metabolomics) and on immunoassays (biosensors) to monitor human exposure to environmental contaminants. We currently are using recombinant alpaca nanobodies in biosensor formats.


1973 PhD Entomology (Toxicology) University of California, Berkeley
1969 BS Entomology (Chemistry) Louisiana State University

Research Interests

See laboratory publications on web site for current areas.

Technically we are a diverse laboratory applying a variety of tools in biological chemistry to questions in regulatory biology.  We attempt to relate our fundamental work to human and environmental health.  The technologies include enzymology, physiology, medicinal chemistry, analytical chemistry and others.


Member National Academy of Sciences
National Academy of Inventors
Alexander von Humboldt Award in International Agriculture
Brodie Award in Xenobiotic Metablism
See resume on web site

Department and Center Affiliations

Director NIH Training Grant in Biotechnology
Principal Investigator NIEHS Superfund Basic Research Program
Department of Entomology & Cancer Research Center


Gold Country Paddlers
Sierra Club
see web site

CBS Grad Group Affiliations

Biochemistry, Molecular, Cellular and Developmental Biology

Graduate Groups not Housed in CBS

Pharmacology and Toxicology, , Agricultural and Environmental Chemistry


Everson Hall Mass Spectrometry Center

Teaching Interests

Mechanism of action of toxins. Development of pharmaceuticals. Biological chemistry. General biochemistry and physiology. Protein purification. Immunoassay.


ETO 214 Mechanisms of Toxic Action (Spring)

Personal Interests

Teach White Water Kayaking through Outdoor Adventures


5/21/2010 9:26:34 AM
  • 646. Ai, D., Y. Fu, D. Guo, H. Tanaka, N. Wang, C. Tang, B.D. Hammock, J.Y-J. Shyy and Y. Zhu. 2007. Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. P. Natl. Acad. Sci. USA. 104:9018-9023.
  • For current publication see laboratory web site.